Effect of Technology-Assisted Preoperative Home Exercise on Postoperative Handgrip Strength, Muscle Endurance, and Psychological Distress in Patients With Pulmonary Nodules Undergoing Video-Assisted Thoracoscopic Surgery

NCT07302217 | Not Yet Recruiting

• 1 other identifier: 202509080RINB
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the effects of a technology-assisted preoperative home-based exercise program, delivered through a LINE Official Account and LINE BOT, on postoperative hand-grip strength, muscle endurance, and psychological distress in patients undergoing thoracoscopic pulmonary nodule resection. The study adopts a single-group pretest post-test design and plans to recruit 60 eligible patients. The intervention consists of at least one week of home exercise training before surgery, incorporating aerobic, resistance, and breathing exercises. Education, guidance, and interactive feedback are provided through the LINE platform to support adherence and exercise performance. Outcomes will be assessed at three time points: baseline (T0), immediately before surgery (T1), and two weeks after surgery (T2).

Conditions

Pulmonary Nodules

Keywords

exercise; APP LINE; Lung nodule

Outcome Measures

Primary Outcomes (1)

• Hand-grip Strength

  Hand-grip strength will be measured using a calibrated handheld dynamometer. Measurements will be collected at three time points: Baseline at outpatient visit when surgery is scheduled (T0), Preoperative assessment on the day of admission (T1), Two weeks after surgery (T2). The primary outcome is the change in dominant-hand grip strength from T0 to T2. Higher values indicate greater muscle strength. The measure reflects postoperative functional recovery and the effectiveness of the technology-assisted preoperative exercise program.

  Before surgery (T0) to 2 weeks post-surgery (T2)

Study Arms (1)

Technology-Assisted Preoperative Home-Based Exercise Program

EXPERIMENTAL

Participants in this arm will receive a technology-assisted preoperative home-based exercise program delivered through a LINE APP. The program includes aerobic, resistance, and breathing exercises performed for at least one week before surgery. Educational messages, reminders, and interactive feedback are provided through the LINE platform to support exercise adherence.

Behavioral: Technology-Assisted Preoperative Home-Based Exercise Program

Interventions

Technology-Assisted Preoperative Home-Based Exercise Program BEHAVIORAL

This behavioral intervention uses a technology-assisted approach to deliver preoperative home-based exercise training for patients scheduled to undergo video-assisted lung nodule resection. The intervention integrates a LINE Official Account with an automated LINE Bot that provides exercise instructions, educational materials, reminders, and self-report mechanisms. The exercise program is based on published preoperative home-exercise protocols for lung cancer surgery patients. It includes: 1. Aerobic exercise - walking or marching in place for 30 minutes, three times per week; 2. Resistance training - six exercises (high-knee marching, bridging, sit-to-stand, shoulder press, biceps curl, heel raise), performed twice weekly (non-consecutive), 30 repetitions each; 3. Breathing exercises - pursed-lip and diaphragmatic breathing, 10 repetitions each, three times per week; 4. Warm-up and cool-down for 5 minutes before and after exercise. The LINE Bot system provides video demonstration

Technology-Assisted Preoperative Home-Based Exercise Program

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with pulmonary nodules who are scheduled to undergo video-assisted thoracoscopic surgery for nodule resection (including wedge resection, segmentectomy, or lobectomy).
• Aged 20 years or older and assessed by a healthcare provider as medically suitable to participate in exercise training.
• At least one week between the date of enrollment and the scheduled surgery.
• Willing to provide written informed consent and complete all study procedures, including joining the LINE Official Account, participating in the exercise training, completing questionnaires, and undergoing outcome assessments.

You may not qualify if:

• Metastatic tumors or contraindications to exercise participation.
• Engagement in regular aerobic or resistance exercise within the past month (defined as ≥2 sessions per week, ≥30 minutes per session).
• Inability to communicate in Mandarin or Taiwanese.
• Inability to use technology-assisted applications (e.g., LINE APP).

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Cancer Center

Taipei, Taiwan

Location

MeSH Terms

Conditions

Multiple Pulmonary Nodules; Motor Activity

Condition Hierarchy (Ancestors)

Lung Neoplasms; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Behavior

Central Study Contacts

Li-Ping Chen, RN, NP

CONTACT

886-2--23123456#238070; A00727@ntucc.gov.tw

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Masking Details: No masking was implemented because all participants and investigators were aware of the intervention procedures.
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This study uses a single-group assignment model without a control group. All participants receive the LINE-based preoperative exercise intervention, and outcomes are compared across baseline, pre-surgery, and two-week postoperative assessments.

Study Record Dates

• First Submitted: December 11, 2025
• First Posted: December 24, 2025
• Study Start: December 17, 2025
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: December 24, 2025

Record last verified: 2025-12

Locations

TW (1)