NCT07278778

Brief Summary

This study invites parents of children with cancer to use an electronic health record (EHR)-based communication tool, called the Cancer Care Companion, and assess the acceptability, appropriateness, and feasibility of the tool.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
16mo left

Started Feb 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress16%
Feb 2026Aug 2027

First Submitted

Initial submission to the registry

December 5, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

December 12, 2025

Completed
2 months until next milestone

Study Start

First participant enrolled

February 4, 2026

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 31, 2027

Last Updated

February 6, 2026

Status Verified

February 1, 2026

Enrollment Period

1.6 years

First QC Date

December 5, 2025

Last Update Submit

February 5, 2026

Conditions

Pediatric Cancer

Keywords

communicationelectronic medical recordpediatric cancer

Outcome Measures

Primary Outcomes (1)

  • Tool feasibility

    The number of tasks marked "complete" divided by total tasks delivered, reported as a percentage per participant, with success defined as meeting or exceeding a 70% completion rate.

    Immediately post-intervention

Secondary Outcomes (9)

  • Information Exchange

    Baseline and immediately post-intervention

  • Trust in Physicians

    Baseline and immediately post-intervention

  • Ability to navigate the healthcare system

    Baseline and immediately post-intervention

  • Caregiver burden

    Baseline and immediately post-intervention

  • Parental anxiety

    Baseline and immediately post-intervention

  • +4 more secondary outcomes

Study Arms (1)

All Participants

EXPERIMENTAL

All participants receive the Cancer Care Companion program. There is no control or comparison group.

Other: Cancer Care Companion

Interventions

Cancer Care CompanionOTHER

The investigators will provide parents access the Cancer Care Companion through Epic MyChart. If a participant has not enrolled in MyChart, the investigator will provide instructional materials and assist with registration. Parents will use the Cancer Care Companion for 3 months during which they will complete tasks including educational modules, check-in surveys, and patient stories. Participants may opt-out of receiving the patient stories. During the 3-month intervention, participants will receive 13 educational tasks, 7 check-in surveys, and 5 patient stories (if requested). The Day 1 educational task will include an overview of the program and further instructions. After enrollment, participants will retain access to Cancer Care Companion for at least 3 months, during which they can revisit the content.

All Participants

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Eligibility Criteria for Parents: Parents of children with cancer will be enrolled if they meet the following criteria: * They are a legal guardian of a child diagnosed with cancer in the prior 4 weeks. * The child plans to receive or currently receives cancer directed therapy at St. Louis Children's Hospital. * The parent or legal guardian has access to internet through a computer or smart phone. * Speaks and reads in English * The parent or legal guardian agrees to enroll in Epic MyChart to access a proxy portal for their child. Eligibility Criteria for Clinicians: * Clinicians with patients who have parents participating may be enrolled. Clinician participants will be employed at SLCH or Washington University School of Medicine (WUSM). The clinicians will include physicians, nurse practitioners, and nurse coordinators from the leukemia/lymphoma, brain tumor, and solid tumor teams in order to represent the breadth of pediatric cancer diagnoses.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Washington University School of Medicine/Saint Louis Children's Hospital

St Louis, Missouri, 63110, United States

RECRUITING

Related Links

MeSH Terms

Conditions

NeoplasmsCommunication

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Bryan A Sisk, MD, MSCI

    Washington University School of Medicine

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Bryan A Sisk, MD, MSCI

CONTACT

314-273-9084siskb@wustl.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 5, 2025

First Posted

December 12, 2025

Study Start

February 4, 2026

Primary Completion (Estimated)

August 31, 2027

Study Completion (Estimated)

August 31, 2027

Last Updated

February 6, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

All data will be submitted to the Qualitative Data Repository at Syracuse University.

Shared Documents
STUDY PROTOCOL, ICF

Locations

US(1)