NCT07249359

Brief Summary

Virtual reality (VR) is a promising non-pharmacological approach to reduce dental anxiety in children with neurodevelopmental disorders. This randomized controlled trial compared a VR-based distraction intervention with conventional monitor-based distraction in children aged 11-15 years with mild intellectual disability and moderate dental anxiety undergoing conservative dental treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
56

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2025

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2025

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2025

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 17, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 25, 2025

Completed
Last Updated

December 3, 2025

Status Verified

November 1, 2025

Enrollment Period

5 months

First QC Date

November 17, 2025

Last Update Submit

November 25, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Treatment success

    Number of patients with completion of restorative dental procedure under local anesthesia within 50 minutes and positive overall treatment experience (dichotomous: success vs. failure)

    Duration of procedure

Study Arms (2)

Virtual Reality Distraction

EXPERIMENTAL

immersive VR software delivered through Meta Quest 3® headset during dental procedure

Device: Virtual Reality Distraction - immersive VR software delivered through Meta Quest 3® headset during dental procedure

Control: Monitor-Based Distraction

ACTIVE COMPARATOR

cartoon video displayed in front of dental chair

Device: Control: Monitor-Based Distraction

Interventions

immersive VR software delivered through Meta Quest 3® headset during dental procedure

Virtual Reality Distraction

cartoon video displayed in front of dental chair

Control: Monitor-Based Distraction

Eligibility Criteria

Age11 Years - 15 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Age 11-15; diagnosis of mild intellectual disability (DSM-5)
  • Moderate anxiety (Corah DAS 9-12)
  • ≥1 decayed tooth requiring conservative treatment under local anesthesia
  • Informed consent from parents/legal guardians

You may not qualify if:

  • no or slight anxiety
  • high or severe anxiety
  • visual disorders
  • neuromuscular comorbidities interfering with cooperation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IRCCS Ass. Oasi Maria SS

Troina, EN, 94018, Italy

Location

MeSH Terms

Conditions

Intellectual Disability

Condition Hierarchy (Ancestors)

Neurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsNeurodevelopmental DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 17, 2025

First Posted

November 25, 2025

Study Start

February 1, 2025

Primary Completion

June 30, 2025

Study Completion

September 30, 2025

Last Updated

December 3, 2025

Record last verified: 2025-11

Locations