Pilot Study, Aimed at Describing in Myography, the Collapse of the Muscular Response Visualized in the Scratch Collapse Test, in Carpal Tunnel Syndrome.

NCT07248124 | Recruiting

• 2 other identifiers: SC-My2025-A01019-40
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve tunnel syndromes. It first involves applying a sensory stimulus to the skin over the suspected nerve compression point, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the healthy side. This loss of strength is transient and disappears after a few seconds. This test can be performed during a patient's clinical examination, with the physician assessing strength or, conversely, muscle collapse. However, while several articles have described the relevance of this test, as well as its sensitivity and specificity, no study has specifically investigated and measured this observed loss of eccentric muscle tone and its unilateral and transient nature, even though the phenomenon of CSP (cutaneous silent period) has been described. We therefore propose to analyze the myographic tracing obtained in patients diagnosed with unilateral carpal tunnel syndrome. A transient loss of muscle tone is expected by selective needle myography on the pathological side after cutaneous sensory stimulation of the wrist, while cutaneous sensory stimulation on the healthy side does not alter the tracings obtained by myography.

Conditions

Carpal Tunnel Syndrome (CTS)

Outcome Measures

Primary Outcomes (1)

• Evolution of the myographic tracings

  Evolution of the myographic tracings (of the infraspinatus muscle) of the pathological arm immediately after ipsilateral stimuli compared to the basic tracings (before stimuli) of the pathological arm and evolution of the myographic tracings of the pathological arm 20 seconds after ipsilateral stimuli compared to the basic tracings (before stimuli) of the pathological arm.

  one day

Study Arms (1)

Patient with unilateral carpal tunnel syndrome

EXPERIMENTAL

Patient with clinical unilateral carpal tunnel syndrome diagnosed by history, clinical examination and electromyography,

Procedure: electromyograph; Diagnostic Test: Scratch Collapse Test

Interventions

electromyograph PROCEDURE

This examination uses electrodes placed along the path of the median nerve to measure the transmission of nerve impulses (conduction studies). It is performed on both hands to compare the results.

Patient with unilateral carpal tunnel syndrome

Scratch Collapse Test DIAGNOSTIC_TEST

The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve canal syndromes. It involves first performing a sensory stimulus on the skin at the suspected nerve compression site, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the stimulated side.

Patient with unilateral carpal tunnel syndrome

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient over 18 years old
• Patient with clinical unilateral carpal tunnel syndrome diagnosed by history, clinical examination and electromyography,
• Patient who has been informed and has given their free, informed, and written consent,
• Patient affiliated with or beneficiary of a social security scheme.

You may not qualify if:

• Other associated canal syndrome on either side (ulnar, defilement, lacertus),
• Rotator cuff pathology, insufficiency or rupture of the infraspinatus,
• Associated cervical pathology,
• Neuropathy, central or peripheral neurological disease,
• Diabetic patient,
• Patient with cognitive impairments that prevent the understanding of the study information,
• Refusal to participate in the study,
• Pregnant, parturient, or breastfeeding woman,
• Patient under legal protection,
• Patient not receiving health protection,
• Protected patient: adult under guardianship, curatorship, or other legal protection, deprived of liberty by judicial or administrative decision

Sponsors & Collaborators

• Elsan: lead

Study Sites (1)

Clinique de l'Ormeau

Tarbes, 65000, France

RECRUITING

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Central Study Contacts

Vincent Martinel, Dr

CONTACT

0033562563895; drvmartinel@goop65.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 17, 2025
• First Posted: November 25, 2025
• Study Start: November 4, 2025
• Primary Completion: May 4, 2026
• Study Completion: May 5, 2026
• Last Updated: November 25, 2025

Record last verified: 2025-11

Locations

FR (1)