NCT07352189

Brief Summary

This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic upper abdominal surgery under general anesthesia. Postoperative pain scores, analgesic consumption and recovery parameters were evaluated during the first 24 hours after surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2023

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 11, 2023

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 15, 2023

Completed
2.6 years until next milestone

First Submitted

Initial submission to the registry

January 11, 2026

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 20, 2026

Completed
Last Updated

January 21, 2026

Status Verified

January 1, 2026

Enrollment Period

5 months

First QC Date

January 11, 2026

Last Update Submit

January 18, 2026

Conditions

Postoperative Pain Management

Keywords

Transversus Abdominis Plane BlockTAP blockPostoperative Painanalgesia

Outcome Measures

Primary Outcomes (1)

  • Postoperative pain score (NRS)

    Postoperative pain intensity measured using the Numeric Rating Scale (NRS), a 0-10 scale where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicates worse pain.

    First 24 hours postoperatively

Study Arms (2)

Ultrasound-guided TAP block (Group U)

EXPERIMENTAL

Patients receiving ultrasound-guided subcostal transversus abdominis plane block for postoperative analgesia.

Procedure: Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block

Laparoscopy-guided TAP block (Group L)

EXPERIMENTAL

Patients receiving laparoscopy-guided transversus abdominis plane block for postoperative analgesia.

Procedure: Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block

Interventions

Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) BlockPROCEDURE

Bilateral laparoscopy-guided transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL 0.25% bupivacaine and 10 ml of 1% lidocaine).

Laparoscopy-guided TAP block (Group L)
Ultrasound-guided Transversus Abdominis Plane (US-TAP) BlockPROCEDURE

Bilateral ultrasound-guided subcostal transversus abdominis plane block performed prior to extubation using a total of 40 mL local anesthetic solution (30 mL0.25% bupivacaine and 10 ml of 1% lidocaine).

Ultrasound-guided TAP block (Group U)

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients aged 18-70 yeras
  • ASA physical status I-III
  • Scheduled for laparoscopic upper abdominal surgery
  • Provided written informed consent

You may not qualify if:

  • Patient refusal
  • Allergy to local anesthetics
  • Coagulopathy
  • Infection at the injection site
  • Severe systemic disease
  • ASA physical status IV-V

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Maltepe University Faculty of Medicine Hospital

Istanbul, Istanbul, 34000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Pain, PostoperativeAgnosia

Interventions

Dental Occlusion

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsPerceptual DisordersNeurobehavioral ManifestationsNervous System Diseases

Intervention Hierarchy (Ancestors)

DentistryDental Physiological PhenomenaDigestive System and Oral Physiological Phenomena

Study Officials

  • Talat Ercan E Şerifsoy, MD

    Maltepe University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 11, 2026

First Posted

January 20, 2026

Study Start

January 11, 2023

Primary Completion

June 15, 2023

Study Completion

June 15, 2023

Last Updated

January 21, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)