Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

NCT07240961 | Recruiting DMC

• 1 other identifier: IMKO-CE 115/2024
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The Erector Spinae Plane (ESP) block or spinal erector block was first described in September 2016 by a Canadian team. It's a block that was initially used for the treatment of chronic thoracic neuropathic pain. The ESP block is one of the inter-fascicular blocks and it's an easy-to-perform technique.In the literature, it has been reported that Lumbar ESPB provides effective analgesia after a hip surgery. The purpose of this prospective randomized study was to compare the analgesic effects of the ultrasound-guided lumbar Erector Spinae Plane block on postoperative pain management versus the multimodal analgesia after total hip arthroplasty.

Conditions

Total Hip Arthroplasty (THA)

Keywords

hip arthroplasty; Lumbal Erector Spinae Plane Block; pain managment

Outcome Measures

Primary Outcomes (1)

• morphine consumption

  total morphine dose

  Day 1

Secondary Outcomes (6)

• pain scores

  Hour 2, Hour 4, Hour 6, Hour 12, Hour 18, Hour 24 and on Day 2 and Day 7.

• intraoperative opioid consumption

  end of surgery

• pain on sitting position

  Day 1

• QR 9 score

  Day 2

• ROM

  Day 1

Study Arms (2)

hip arthroplasty with nerve block

ACTIVE COMPARATOR

Lumbar ESP block performed after anesthesia induction. A low-frequency ultrasound probe will be placed longitudinally 2-3 cm lateral to the L4 transverse process. Erector spinae muscle will be visualized on the hyperechoic transverse process. The block needle (100 mm, 22G) will be inserted cranio-caudal direction and following confirmation of the correct position of the needle, between the erectorspinae muscle and the transverse process,30 ml of local anesthetic (0.25% bupivacaine/0.2% ropivacaine) will be administered for the block

Procedure: Lumbal Erector Spinae Plane Block

hip arthroplasty with intravenous pain killers

PLACEBO COMPARATOR

intravenous pain killers

Procedure: intravenous pain killers

Interventions

Lumbal Erector Spinae Plane Block PROCEDURE

Lumbar ESP block performed after anesthesia induction. A low-frequency ultrasound probe will be placed longitudinally 2-3 cm lateral to the L4 transverse process. Erector spinae muscle will be visualized on the hyperechoic transverse process. The block needle (100 mm, 22G) will be inserted cranio-caudal direction and following confirmation of the correct position of the needle, between the erectorspinae muscle and the transverse process,30 ml of local anesthetic (0.25% bupivacaine/0.2% ropivacaine) will be administered for the block.

hip arthroplasty with nerve block

intravenous pain killers PROCEDURE

intravenous pain killers

hip arthroplasty with intravenous pain killers

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• primary total hip arthroplasty with lateral approach and under general anesthesia .

You may not qualify if:

• Contraindication or refusal to regional anesthesia
• Contraindication to non-steroidal anti-inflammatory (NSAID's)
• Allergy to opioids
• Allergy to paracetamol
• Creatinine clearance \< 30ml/min
• Weight\<50 kg or \>100kg
• Psychiatric disorders and difficulty of communication
• Lower limb neurological deficit
• Patients undergoing bilateral or revision total hip replacement

Sponsors & Collaborators

• University Tunis El Manar: lead

Study Sites (1)

Kassab Orthopedic Institute

Manouba, 2010, Tunisia

RECRUITING

Central Study Contacts

KAABACHI OLFA

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor

Study Record Dates

• First Submitted: May 1, 2025
• First Posted: November 21, 2025
• Study Start: November 1, 2025
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): July 7, 2026
• Last Updated: November 21, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)