NCT07550647

Brief Summary

This study aims to investigate the effects of an early postoperative rehabilitation program combined with neuromuscular electrical stimulation (NMES) and telerehabilitation on functional recovery in patients undergoing total hip arthroplasty (THA). In the early postoperative period, patients commonly experience muscle weakness, impaired gait, and functional limitations that may delay recovery. Early rehabilitation has been shown to improve functional outcomes, while NMES may enhance muscle activation, particularly in hip abductor muscles. Additionally, telerehabilitation may support continuity of care following discharge by enabling supervised home-based exercise. In this prospective study, participants will be assigned to either an intervention group receiving early physiotherapy combined with NMES and telerehabilitation, or a control group receiving standard postoperative care. Functional outcomes, gait parameters, quality of life, and muscle-related changes will be evaluated at predefined time points.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
17mo left

Started Apr 2026

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress7%
Apr 2026Oct 2027

First Submitted

Initial submission to the registry

March 30, 2026

Completed
2 days until next milestone

Study Start

First participant enrolled

April 1, 2026

Completed
23 days until next milestone

First Posted

Study publicly available on registry

April 24, 2026

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2027

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2027

Last Updated

April 24, 2026

Status Verified

April 1, 2026

Enrollment Period

1.2 years

First QC Date

March 30, 2026

Last Update Submit

April 19, 2026

Conditions

Total Hip Arthroplasty (THA)

Keywords

RehabilitationTotal Hip Arthtoplasty

Outcome Measures

Primary Outcomes (3)

  • Timed Up and Go (TUG) Test

    Functional mobility will be assessed using the Timed Up and Go (TUG) test. The time required to stand up from a chair, walk 3 meters, turn, return, and sit down will be recorded in seconds.

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4.

  • 10-Meter Walk Test (10MWT)

    Gait speed will be assessed using the 10-Meter Walk Test. Walking speed will be recorded in meters per second (m/s).

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4

  • Stair Climb Test

    Functional lower extremity performance will be assessed using the Stair Climb Test. The time required to ascend and descend a standardized flight of stairs will be recorded in seconds.

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4

Secondary Outcomes (9)

  • 6-Minute Walk Test (6MWT)

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4

  • Hip Muscle Strength (Manual Muscle Testing)

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4

  • Range of Motion (ROM)

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4

  • Pain Intensity (Visual Analog Scale - VAS)

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4

  • Hip Function and Quality of Life (International Hip Outcome Tool-12)

    Preoperative (within 3 days before surgery), postoperative day 6 (at discharge), and postoperative week 4

  • +4 more secondary outcomes

Study Arms (2)

Experimental Group (Early Physiotherapy + NMES + Telerehabilitation)

EXPERIMENTAL

Participants will receive a structured physiotherapy program initiated on the first postoperative day, including exercise and neuromuscular electrical stimulation (NMES) targeting the gluteus medius during hospitalization (5 days). After discharge, the intervention will continue with a 3-week home-based exercise program supported by synchronous telerehabilitation sessions conducted three times per week.

Other: Early Postoperative PhysiotherapyDevice: Neuromuscular Electrical Stimulation (NMES)Other: Telerehabilitation

Control Group (Standard Care)

ACTIVE COMPARATOR

Participants will receive the hospital's standard postoperative care during hospitalization, including routine monitoring and wound care without a structured physiotherapy program. At discharge, they will be provided with a home exercise brochure with instructions but will not receive supervised telerehabilitation.

Other: Standard Postoperative Care

Interventions

Early Postoperative PhysiotherapyOTHER

A structured physiotherapy program including mobilization and therapeutic exercises initiated on postoperative day 1 and continued daily until discharge (5 days).

Experimental Group (Early Physiotherapy + NMES + Telerehabilitation)
Neuromuscular Electrical Stimulation (NMES)DEVICE

NMES applied to the gluteus medius muscle starting on postoperative day 1, administered daily for 5 days using standard stimulation parameters to enhance muscle activation.

Experimental Group (Early Physiotherapy + NMES + Telerehabilitation)
TelerehabilitationOTHER

A 3-week home-based exercise program supported by synchronous video-based telerehabilitation sessions conducted three times per week after discharge.

Experimental Group (Early Physiotherapy + NMES + Telerehabilitation)
Standard Postoperative CareOTHER

Routine postoperative care including wound monitoring and general medical follow-up during hospitalization. At discharge, patients receive a home exercise brochure without supervised rehabilitation or telerehabilitation.

Control Group (Standard Care)

Eligibility Criteria

Age50 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients scheduled for unilateral total hip arthroplasty due to osteoarthritis or developmental dysplasia of the hip (DDH)
  • Aged between 50 and 75 years
  • Willing and able to participate in all follow-up assessments
  • Able to comply with assessment procedures
  • Able to meet the requirements of telerehabilitation
  • Undergoing surgery with a standardized surgical protocol

You may not qualify if:

  • Previous history of total hip arthroplasty on either side
  • Planned revision total hip arthroplasty
  • Severe osteoarthritis in the contralateral hip
  • Presence of severe acute metabolic, neuromuscular, or cardiovascular disease
  • History of active malignancy
  • Presence of respiratory infection
  • Concomitant orthopedic conditions (e.g., lower extremity fractures, severe hip/knee deformities, lumbar or sacroiliac dysfunction)
  • Body mass index \>35
  • Occurrence of postoperative complications (e.g., prosthetic infection, thromboembolic events, or conditions requiring reoperation)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Niğde Ömer Halisdemir University, Education and Research Hospital

Niğde, Merkez, 51200, Turkey (Türkiye)

RECRUITING

Related Publications (4)

  • Baldwin EB, et al. Wide-pulse-width, high-frequency neuromuscular stimulation: implications for functional electrical stimulation. J Appl Physiol. 2006;101(1):228-240.

    BACKGROUND

  • Marchisio AE, et al. Accelerated rehabilitation versus conventional rehabilitation in total hip arthroplasty: A randomized double blinded clinical trial. Rev Col Bras Cir. 2020;47:e20202548.

    BACKGROUND

  • Madara KC, et al. Progressive rehabilitation after total hip arthroplasty: A pilot and feasibility study. Int J Sports Phys Ther. 2019;14(4):564-581.

    BACKGROUND

  • Monaghan B, Grant T, Hing W, Cusack T. Functional exercise after total hip replacement (FEATHER): a randomised control trial. BMC Musculoskelet Disord. 2012 Nov 28;13:237. doi: 10.1186/1471-2474-13-237.

    PMID: 23190932BACKGROUND

MeSH Terms

Interventions

Telerehabilitation

Intervention Hierarchy (Ancestors)

RehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and ServicesTelemedicineDelivery of Health CarePatient Care ManagementHealth Services Administration

Central Study Contacts

Cansu Dal, Specialist Physiotherapist

CONTACT

+905379773071ptcansudal@gmail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
The study was designed as a single-blind randomized controlled trial in which outcome assessments were performed by an independent and experienced physiotherapist blinded to group allocation.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: 2 groups with two different applications
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Specialist Physiotherapist

Study Record Dates

First Submitted

March 30, 2026

First Posted

April 24, 2026

Study Start

April 1, 2026

Primary Completion (Estimated)

July 1, 2027

Study Completion (Estimated)

October 1, 2027

Last Updated

April 24, 2026

Record last verified: 2026-04

Locations

TU(1)