The Effect of LymphaTouch® and Manual Lymphatic Drainage on Extremity Circumference Measurements in Lymphedema

NCT07240324 | Completed

• 1 other identifier: istftreah2
• Study Type: observational
• Target: 172
• Locations: 1 country
• Sites: 1

Brief Summary

This retrospective study will be conducted using the medical records of lymphedema patients followed in the Physical Medicine and Rehabilitation outpatient clinics and lymphedema unit of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. Women and men aged 18-75 years with a diagnosis of upper or lower extremity lymphedema will be included. Sociodemographic and clinical data of the patients will be recorded, and participants will be divided into two treatment groups: those who received LymphaTouch® therapy and those who underwent Manual Lymphatic Drainage (MLD). Pre- and post-treatment extremity circumference measurements will be obtained from patient records, and the differences between the groups will be compared.

Conditions

Lymphedema

Outcome Measures

Primary Outcomes (1)

• Change in Extremity Circumference (cm):

  he primary outcome will be the difference in limb circumference measurements before and after treatment. Circumference values will be obtained from standardized anatomical landmarks, including the wrist/ankle, and at 10 cm, 20 cm, 30 cm, and 40 cm proximal to the metatarsophalangeal (MTP) or metacarpophalangeal (MCP) joint. A greater reduction in circumference indicates a more effective treatment response.

  Baseline

Study Arms (2)

MLD group

Patients with lympedema who received MLD treatment

Other: No intervention

Lymphatouch group

Patients with lympedema who received Lymphatouch treatment

Other: No intervention

Interventions

No intervention OTHER

No intervention

Lymphatouch group; MLD group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

ChatGPT: The study population consists of patients with lymphedema who received either LymphaTouch® or Manual Lymphatic Drainage (MLD) treatment.

You may qualify if:

• Clinically diagnosed with lymphedema
• Aged between 18 and 75 years
• Complete pre- and post-treatment extremity circumference measurements available in patient records

You may not qualify if:

• History of systemic diseases such as diabetes, rheumatologic disorders, or malignancy
• Presence of neurological disorders (e.g., polyneuropathy, multiple sclerosis, history of stroke)
• Pregnancy
• History of surgery or major trauma involving the affected limb within the past 6 months
• History of injection therapy or physical therapy applied to the same limb within the past 6 months
• History of infection or active dermatological disease affecting the limb
• Incomplete or inconsistent data in patient records

Sponsors & Collaborators

• Istanbul Physical Medicine Rehabilitation Training and Research Hospital: lead

Study Sites (1)

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Istanbul, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Lymphedema

Condition Hierarchy (Ancestors)

Lymphatic Diseases; Hemic and Lymphatic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Target Duration: 1 Day
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 16, 2025
• First Posted: November 20, 2025
• Study Start: October 10, 2025
• Primary Completion: October 10, 2025
• Study Completion: November 10, 2025
• Last Updated: November 20, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)