Living Well With Advanced Breast Cancer

NCT07227038 | Recruiting

• 2 other identifiers: OSU-24331NCI-2025-08030
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the use of supportive care in patients with advanced breast cancer to better understand what has helped them, what has been hard, and what kind of help they still need.

Conditions

Advanced Breast Carcinoma; Anatomic Stage IV Breast Cancer AJCC v8; Metastatic Breast Carcinoma

Outcome Measures

Primary Outcomes (3)

• Acceptability of current LWABC (Living Well with Advanced Breast Cancer) model

  Will utilize a thematic inductive analysis approach to compare and contrast themes across cohorts. Survey items will be summarized by cohort. Means, standard deviations, medians and ranges will be calculated for continuous variables and frequency, percents and 95% confidence intervals will be calculated for categorical variables.

  Up to study completion, up to 1 day

• Participant medical history, treatment records, and demographic data

  Will utilize a thematic inductive analysis approach to compare and contrast themes across cohorts. Survey items including demographic information and disease characteristics will be summarized by cohort. Means, standard deviations, medians and ranges will be calculated for continuous variables and frequency, percents and 95% confidence intervals will be calculated for categorical variables.

  Up to study completion, up to 1 day

• Differences in survivorship care engagement across four distinct cohorts

  Will utilize a thematic inductive analysis approach to compare and contrast themes across cohorts. Themes will be compared across each cohort to identify survivorship care needs that will be translated into intervention components for the ABC survivorship program. Survey items will be summarized by cohort. Means, standard deviations, medians and ranges will be calculated for continuous variables and frequency, percents and 95% confidence intervals will be calculated for categorical variables.

  Up to study completion, up to 1 day

Study Arms (1)

Observational

Patients complete a survey and a semi-structured interview on study.

Other: Non-Interventional Study

Interventions

Non-Interventional Study OTHER

Non-interventional study

Also known as: Non-Interventional Observational Study, Noninterventional (Observational) Study

Observational

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with advanced breast cancer and their caregivers recruited through Ohio State University Comprehensive Cancer Center

You may qualify if:

• \* COHORT 1:
• Diagnosis of stage 4 metastatic breast cancer within the past 5 years
• Never been referred to the LWABC
• Adults age ≥ 18 years
• COHORT 2:
• Diagnosis of stage 4 metastatic breast cancer within the past 5 years
• Have cancelled an appointment with the LWABC
• Adults age ≥ 18 years
• COHORT 3:
• Been seen in the Medical Oncology Clinic at Stephanie Spielman Comprehensive Breast Center (SSCBC) within the past 5 years
• Completed an appointment with the LWABC
• Adults age ≥ 18 years
• COHORT 4:
• Caregivers for ABC patients
• Adults age ≥ 18 years

You may not qualify if:

• Patients who cannot provide own informed consent

Sponsors & Collaborators

• Ohio State University Comprehensive Cancer Center: lead
• Lilly Foundation: collaborator

Study Sites (1)

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States

RECRUITING

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases

Study Officials

• Ashley P Davenport, MD

  Ohio State University Comprehensive Cancer Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

The Ohio State University Comprehensive Cancer Center

CONTACT

800-293-5066; OSUCCCClinicaltrials@osumc.edu

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 7, 2025
• First Posted: November 12, 2025
• Study Start: January 13, 2026
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: March 19, 2026

Record last verified: 2026-03

Locations

US (1)