Key Insights

Highlights

Success Rate

62% trial completion

Published Results

28 trials with published results (21%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 47/100

Termination Rate

11.1%

15 terminated out of 135 trials

Success Rate

61.5%

-25.0% vs benchmark

Late-Stage Pipeline

4%

6 trials in Phase 3/4

Results Transparency

117%

28 of 24 completed with results

Key Signals

28 with results62% success15 terminated

Data Visualizations

Phase Distribution

124Total
Not Applicable (14)
Early P 1 (7)
P 1 (51)
P 2 (46)
P 3 (5)
P 4 (1)

Trial Status

Recruiting43
Active Not Recruiting25
Completed24
Withdrawn20
Terminated15
Suspended5

Trial Success Rate

61.5%

Benchmark: 86.6%

Based on 24 completed trials

Clinical Trials (135)

Showing 20 of 20 trials
NCT05564377Phase 2Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT05751668Phase 2Active Not RecruitingPrimary

Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel

NCT02115282Phase 3Active Not Recruiting

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

NCT04305834Phase 2RecruitingPrimary

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

NCT05422794Phase 1Recruiting

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

NCT06179303Phase 2Recruiting

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

NCT06999798Phase 1Recruiting

An Optimized Ultrasound Twinkling Marker for the Imaging of Lymph Nodes in Patients With Clinically Node-Positive Breast Cancer, The UTMOST2 Trial

NCT01334021Phase 2Active Not Recruiting

Genetic Testing in Predicting Tumor Response in Patients With Stage I-III HER2 Negative Invasive Breast Cancer

NCT04090398Phase 2Active Not RecruitingPrimary

Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones

NCT02453620Phase 1Active Not Recruiting

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

NCT06500455Phase 3Active Not RecruitingPrimary

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

NCT04090567Phase 2Recruiting

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

NCT04316117Phase 2Active Not RecruitingPrimary

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

NCT03606967Phase 2RecruitingPrimary

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

NCT03939897Phase 1Active Not RecruitingPrimary

Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer

NCT04704661Phase 1Active Not Recruiting

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT06055881Not ApplicableActive Not Recruiting

Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy

NCT07594678Phase 2Not Yet Recruiting

Minoxidil With or Without Low-Level Red-Light Therapy for Improving Chemotherapy-Induced Alopecia in Breast Cancer Patients

NCT05756166Phase 1TerminatedPrimary

Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer

NCT06982222Phase 1WithdrawnPrimary

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones

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