Key Insights

Highlights

Success Rate

61% trial completion

Published Results

26 trials with published results (20%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

11.5%

15 terminated out of 130 trials

Success Rate

60.5%

-26.0% vs benchmark

Late-Stage Pipeline

4%

5 trials in Phase 3/4

Results Transparency

113%

26 of 23 completed with results

Key Signals

26 with results61% success15 terminated

Data Visualizations

Phase Distribution

121Total
Not Applicable (14)
Early P 1 (7)
P 1 (50)
P 2 (45)
P 3 (4)
P 4 (1)

Trial Status

Recruiting45
Completed23
Active Not Recruiting20
Withdrawn19
Terminated15
Suspended5

Trial Success Rate

60.5%

Benchmark: 86.5%

Based on 23 completed trials

Clinical Trials (130)

Showing 20 of 20 trials
NCT04647916Phase 2Active Not RecruitingPrimary

Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

NCT05318469Phase 1RecruitingPrimary

Ivermectin in Combination With Balstilimab or Pembrolizumab in Patients With Metastatic Triple Negative Breast Cancer

NCT06112613Not ApplicableRecruitingPrimary

Mobile Health for Adherence in Breast Cancer Patients

NCT04316117Phase 2Active Not RecruitingPrimary

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

NCT03179904Phase 2Active Not Recruiting

TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer

NCT04305834Phase 2RecruitingPrimary

Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

NCT06500455Phase 3RecruitingPrimary

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

NCT05564377Phase 2Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

NCT04314401Active Not Recruiting

National Cancer Institute "Cancer Moonshot Biobank"

NCT02115282Phase 3Active Not Recruiting

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

NCT03218826Phase 1Completed

PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery

NCT03939897Phase 1Active Not RecruitingPrimary

Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer

NCT04704661Phase 1Active Not Recruiting

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

NCT06630325Phase 2Terminated

A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer

NCT03606967Phase 2RecruitingPrimary

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

NCT02364557Phase 2Completed

Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival

NCT06434064Phase 2Recruiting

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

NCT06492759Phase 2RecruitingPrimary

High Dose Radiation Therapy With Pembrolizumab and Chemotherapy for the Treatment of Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer

NCT05081492Phase 1Active Not RecruitingPrimary

CF33-hNIS-antiPDL1 for the Treatment of Metastatic Triple Negative Breast Cancer

NCT06179303Phase 2Recruiting

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

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