Digital Phenotyping for Psychosocial Screening in Adolescents and Young Adults With Cancer

NCT07220343 | Recruiting

• 1 other identifier: IRB-73748
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The overall goal of the proposed study is to use digital phenotyping to identify and triage at-risk patients and accelerate access to critical mental health services.

Conditions

Cancer; Adolescents

Keywords

Smartphone; Cancer

Outcome Measures

Primary Outcomes (1)

• Change in Depressive Symptoms (Beck Depression Inventory - BDI)

  The Beck Depression Inventory-II (BDI-II; range 0-63) will be used to measure changes in depressive symptoms among adolescents and young adults over time. Higher scores indicate greater depressive symptom severity.

  Baseline, Day 10, 2 months

Secondary Outcomes (7)

• Participant Retention Rate (MyPHD App and Wearable Device)

  Baseline to 2 months

• Adherence to EMA Prompts

  Baseline to 2 months

• Wearable Device Return and Use Rate

  Baseline to 2 months

• Change in Anxiety Symptoms (Beck Anxiety Inventory - BAI)

  Baseline, Day 10, 2 months

• Change in PTSD Symptoms (CROPS)

  Baseline

Study Arms (1)

Digital Phenotyping Arm

EXPERIMENTAL

All participants (adolescents and young adults with cancer) will receive the digital phenotyping intervention, which includes wearing a smartwatch and using a smartphone-based EMA app over a 10-day period, with psychosocial assessments at baseline, day 10, and 2 months

Device: Device; Behavioral: Ecological Momentary Assessment (EMA) via My Personal Health Dashboard (MyPHD) Smartphone App

Interventions

Device DEVICE

Participants will wear a wrist-based wearable device for 10 days to passively track physiological data (heart rate, steps, sleep, etc.).

Digital Phenotyping Arm

Ecological Momentary Assessment (EMA) via My Personal Health Dashboard (MyPHD) Smartphone App BEHAVIORAL

Participants will respond to ecological momentary assessments (EMA) via smartphone to actively report on sleep, mood, stress, and eating habits across a 10-day period.

Digital Phenotyping Arm

Eligibility Criteria

• Age: 10 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• years old
• Recent cancer diagnosis (\>2 and \<18 months since diagnosis)
• Willing to carry smartphone on their person for duration of study participation
• Willing to wear smartwatch for duration of study participation

You may not qualify if:

• Significant physical or mental disability that prevents completion of study activities
• Lack of proficiency in English or Spanish

Sponsors & Collaborators

• Stanford University: lead

Study Sites (1)

Stanford University

Palo Alto, California, 94304, United States

RECRUITING

MeSH Terms

Conditions

Neoplasms

Interventions

Equipment and Supplies; Ecological Momentary Assessment

Intervention Hierarchy (Ancestors)

Psychological Tests; Behavioral Disciplines and Activities

Study Officials

• Victoria Cosgrove, PhD

  Stanford University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Olivia Borge

CONTACT

(650) 723-9392; oborge@stanford.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 9, 2025
• First Posted: October 23, 2025
• Study Start: January 29, 2025
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: December 30, 2025

Record last verified: 2025-12

Locations

US (1)