Horizontal Anterior Maxillary Ridge Augmentation Using Autogenous Ring Block Grafts Combined With Particulate Xenogeneic Bone Versus Biphasic Beta-tri-calcium Phosphate Sulphate EthOss Graft: A Clinical Study

NCT07212985 | Completed DMC

• 1 other identifier: REC-PD-24-22
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

. Group A, received ABG cylinders obtained from the chin and organic bovine bone mineral particles (Bio-Oss xenograft) along with an absorbable collagen membrane. ABG cylinders from the chin and biphasic alloplastic (EthOss) grafting material made of CS (35%) and TCP (65%) were given to Group B. CBCT scans were conducted before bone augmentation surgery, one week and 6 months postoperatively

Conditions

Implant Dentistry

Outcome Measures

Primary Outcomes (1)

• Change in horizontal alveolar ridge width

  Baseline, 1 week, and 6 months post-surgery

Secondary Outcomes (1)

• Postoperative complications

  Up to 6 months post-surgery

Study Arms (2)

ABG + Xenograft + Collagen Membrane

EXPERIMENTAL

Patients receive autogenous bone block graft (from chin) combined with particulate bovine xenograft (Bio-Oss, Geistlich Pharma AG) and covered with absorbable collagen membrane (Bio-Gide).

Procedure: Autogenous Bone Block + Xenograft + Collagen Membrane

ABG + EthOss (Synthetic Graft)

EXPERIMENTAL

Patients receive autogenous bone block graft (from chin) combined with EthOss, a biphasic synthetic graft material (35% calcium sulfate, 65% β-tricalcium phosphate).

Procedure: Autogenous Bone Block + Xenograft + Collagen Membrane

Interventions

Autogenous Bone Block + Xenograft + Collagen Membrane PROCEDURE

Autogenous chin bone block graft combined with particulate bovine xenograft (Bio-Oss, Geistlich Pharma AG) and covered with an absorbable collagen membrane (Bio-Gide).

ABG + EthOss (Synthetic Graft); ABG + Xenograft + Collagen Membrane

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults ≥18 years requiring implant-supported restoration in the anterior maxilla
• Horizontal alveolar bone deficiency \<4 mm (Cawood \& Howell Class III-IV)
• Satisfactory oral hygiene
• No previous bone augmentation at study site

You may not qualify if:

• Uncontrolled systemic diseases
• History of head/neck irradiation or immunosuppression
• Oral lesions (e.g., lichen planus)
• Ongoing or recent IV bisphosphonate therapy
• Untreated periodontitis or poor oral hygiene
• Parafunctional habits, pregnancy, psychiatric disorders
• Recent tobacco use

Sponsors & Collaborators

• Al-Azhar University: lead

Study Sites (1)

Faculty of Oral and Dental Medicine, Nahda University,Taibah University

Cairo, Egypt

Location

MeSH Terms

Interventions

Transplantation, Heterologous

Intervention Hierarchy (Ancestors)

Transplantation; Surgical Procedures, Operative

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Oral Medicine, Periodontology and Diagnosis, Faculty of Dental Medicine for girls, Al -Azhar University, Cairo, Egypt

Study Record Dates

• First Submitted: October 1, 2025
• First Posted: October 8, 2025
• Study Start: January 5, 2023
• Primary Completion: June 5, 2024
• Study Completion: June 18, 2024
• Last Updated: October 8, 2025

Record last verified: 2025-10

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)