Comparison of Transcutaneous and Arterial Carbon Dioxide Sampling During Jet Ventilation, a Prospective. Study on Patients Undergoing Percutaneous Liver Tumour Radiofrequency Ablation

NCT07211763 | Recruiting FDA Device

• 1 other identifier: LiverJet
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to compare the readings from two methods of monitoring carbon dioxide levels during jet ventilation when normal end-tidal monitoring is not possible. During jet ventilation it is technically not possible to monitor the levels of carbon dioxide in exhaled air as is the standard in preoperative care. We will compare transcutaneous (through the skin) monitoring to an arterial blood. sample. Both transcutaneous monitoring and arterial monitoring is currently used as the standard for this patient group at our institution. By collecting data prospectively we can evaluate if there. are discrepancies based on monitoring method. All patients will be treated per standard preoperative protocol and only patients consenting to participate will contribute data to the comparison and statistical analysis.

Conditions

Liver Ablation; High Frequency Jet Ventilation

Keywords

jet ventilation

Outcome Measures

Primary Outcomes (1)

• Difference in CO2 between TcCO2 and PaCO2

  during perioperative management

Study Arms (1)

jet_ventilation

Other: No Interventions

Interventions

No Interventions OTHER

No intervention, solely data collection

jet_ventilation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adults undergoing percutaneous RF liver ablation under jet ventilation

You may qualify if:

• adult patients undergoing percutaneous RF liver tumour ablation requiring jet ventilation

You may not qualify if:

• disease or condition. not compatible with jet ventilation

Sponsors & Collaborators

• Sahlgrenska University Hospital: lead

Study Sites (1)

Sahlgrenska University Hospital

Gothenburg, Sweden

RECRUITING

Study Officials

• Fredrik Olsen, MD PhD

  Sahlgrenska University Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Fredrik Olsen, MD PhD

CONTACT

+46 313428169; fredrik.olsen@vgregion.se

Carl Hallgren, MD

CONTACT

+460313430286; carl.hallgren@vgregion.se

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD PhD

Study Record Dates

• First Submitted: October 1, 2025
• First Posted: October 8, 2025
• Study Start: April 1, 2025
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: October 8, 2025

Record last verified: 2025-10

Locations

SE (1)