Precision Diabetes Management: Integrated East-West Approach

NCT07307040 | Not Yet Recruiting

• 1 other identifier: CXZH2024059
• Study Type: observational
• Target: 2,000
• Locations: 0 countries
• Sites: N/A

Brief Summary

This project will leverage a large-scale cohort of early-onset type 2 diabetes patients to conduct innovative prospective clinical research. By integrating traditional Chinese medicine diagnostic information, clinical data, laboratory results, continuous glucose monitoring, genetic information, multi-omics data, and multi-modal monitoring data, and utilizing advanced data analysis methods such as deep learning, the project aims to establish a comprehensive monitoring, precise classification, and personalized diagnosis and treatment model-a holistic management approach integrating traditional Chinese and Western medicine for early-onset type 2 diabetes. This initiative is expected to enhance the management of early-onset type 2 diabetes, improve treatment outcomes and quality of life for affected patients, pioneer an innovative path for personalized integrated traditional Chinese and Western medicine management in this population, and promote the application of precision medicine in diabetes prevention and treatment.

Conditions

Early-Onset Type 2 Diabetes

Keywords

Integrated Traditional Chinese and Western Medicine; Precision Management; Personalized Management; Early-Onset Type 2 Diabetes

Outcome Measures

Primary Outcomes (2)

• Traditional Chinese Medicine Syndrome Score

  Through study completion, an average of 3 months

• HbA1c

  Through study completion, an average of 3 months

Secondary Outcomes (5)

• Triglycerides

  Through study completion, an average of 3 months

• High-Density Lipoprotein Cholesterol

  Through study completion, an average of 3 months

• Total Cholesterol

  Through study completion, an average of 3 months

• Fasting Blood Glucose

  Through study completion, an average of 3 months

• Low-Density Lipoprotein Cholesterol

  Through study completion, an average of 3 months

Study Arms (1)

Integrated Traditional Chinese and Western Medicine Management

Other: No interventions

Interventions

No interventions OTHER

No interventions

Integrated Traditional Chinese and Western Medicine Management

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

The age at type 2 diabetes diagnosis is ≥18 years but \<40 years.

You may qualify if:

• The age at diabetes diagnosis is ≥18 years but \<40 years.

You may not qualify if:

• The clinical diagnosis was type 1 diabetes, and at the time of enrollment, antibody levels or insulin/C-peptide results still supported the original diagnosis.
• There were clear secondary factors contributing to hyperglycemia, such as Cushing's syndrome or pheochromocytoma.

Sponsors & Collaborators

• Peking Union Medical College Hospital: lead

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief physician

Study Record Dates

• First Submitted: December 1, 2025
• First Posted: December 29, 2025
• Study Start: December 31, 2025
• Primary Completion (Estimated): March 31, 2027
• Study Completion (Estimated): March 31, 2027
• Last Updated: December 29, 2025

Record last verified: 2025-12