Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia

NCT07211581 | Completed

• 1 other identifier: AlSafwaUC
• Study Type: observational
• Target: 123
• Locations: 1 country
• Sites: 1

Brief Summary

Predicting post-total thyroidectomy hypocalcemia involves a combination of patient-specific, disease-related, and surgical factors. Key predictive factors include the intrinsic characteristics of the thyroid disease, pre-operative levels of calcium and vitamin D, the degree of parathyroid gland manipulation or injury, advanced age, and pre-existing hyperthyroidism. While no single factor is definitive, a low post-operative parathyroid hormone (iPTH) level is a strong indicator of developing hypocalcemia

Conditions

Hypocalcemia After Total Thyroidectomy

Keywords

Predicting Factors.; Total Thyroidectomy.; Hypocalcemia

Outcome Measures

Primary Outcomes (2)

• hypocalcemia incidence

  1 day and 2 weeks after surgery

• hypocalcemia other factors related to clinical status.

  Comparison of Serum Calcium levels of the studied group reported Comparison of PTH levels between hypocaӏcemia and Eucalcemic

  1 day and 2 weeks after surgery

Interventions

total thyroidectomy PROCEDURE

both lobes removed and observe the calcemic level

Eligibility Criteria

• Age: 21 Years - 76 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

A total of 123 patients who underwent total thyroidectomy for various thyroid diseases were included in the study, performed by a group of surgeons.

You may qualify if:

• patients requiring total thyroidectomy.
• age between 18-75 years old
• both gender
• no co-existing disease.

You may not qualify if:

• \. previous hemithyroidectomy, lobectomy, resection of the parathyroid gland. 2. 2. patients with missing laboratory data, previous subtotal thyroidectomy.
• \. diagnosed pathology of the parathyroid gland

Sponsors & Collaborators

• Al Safwa University College: lead

Study Sites (1)

Mustaqbal University

Sfax, Safx, 54001, Tunisia

Location

MeSH Terms

Conditions

Hypocalcemia

Condition Hierarchy (Ancestors)

Calcium Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Water-Electrolyte Imbalance

Study Officials

• 1. Ali Fadhil Zaidan, PhD

  mustaqbal university

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia

Study Record Dates

• First Submitted: September 17, 2025
• First Posted: October 8, 2025
• Study Start: September 17, 2025
• Primary Completion: September 17, 2025
• Study Completion: September 17, 2025
• Last Updated: October 8, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)