Clinical Characteristics of Neovascular Glaucoma

NCT07177807 | Completed

• 1 other identifier: 20250719
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to explore the clinical characteristics of patients with neovascular glaucoma (NVG), and to analyze the relationship between NVG and various underlying diseases, ocular conditions, lifestyle, inflammatory markers, and treatment response. To systematically analyze the clinical data of NVG patients with different types of primary disease, further reveal the different clinical characteristics of NVG patients with different primary disease, and describe the selection of treatment methods in recent years, in order to provide more scientific basis for clinical treatment.

Conditions

Neovascular Glaucoma

Keywords

Neovascular glaucoma; clinical feature; Retinal Vein Occlusion; Diabetic Retinopathy

Outcome Measures

Primary Outcomes (2)

• visual acuity

  best-corrected visual acuity （BCVA）

  Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months, 1 year, etc.

• intraocular pressure

  intraocular pressure(IOP)

  Time Frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 6 months, 1 year, etc.

Study Arms (3)

ALL group

DR group

RVO group

Eligibility Criteria

• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with NVG diagnosed by ophthalmic examination in the Second Clinical Hospital of Wuhan University, Central Hospital of Enshi Tujia and Miao Autonomous Prefecturefrom and Central Hospital of Xiaogan from January 2018 to September 2024 were enrolled. A certain number of healthy volunteers in the Physical Examination Center of the Second Clinical Hospital of Wuhan University from January 2018 to September 2024 were enrolled

You may qualify if:

• Patients who met the diagnostic criteria for NVG.

You may not qualify if:

• Patients with incomplete clinical data and information.
• Severe systemic diseases (such as chronic renal failure requiring dialysis, severe neurological diseases, immune diseases), pregnancy or lactation.

Sponsors & Collaborators

• Zhongnan Hospital: lead
• The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture: collaborator
• Central Hospital of Xiaogan: collaborator

Study Sites (1)

Zhongnan Hospital of Wuhan University

Wuhan, Hubei, 430071, China

Location

MeSH Terms

Conditions

Glaucoma, Neovascular; Retinal Vein Occlusion; Diabetic Retinopathy

Condition Hierarchy (Ancestors)

Glaucoma; Ocular Hypertension; Eye Diseases; Retinal Diseases; Venous Thrombosis; Thrombosis; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Diabetic Angiopathies; Diabetes Complications; Diabetes Mellitus; Endocrine System Diseases

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 10, 2025
• First Posted: September 17, 2025
• Study Start: January 1, 2018
• Primary Completion: September 1, 2024
• Study Completion: September 1, 2024
• Last Updated: September 17, 2025

Record last verified: 2025-09

Locations

CN (1)