NCT00441181

Brief Summary

Prostaglandin analogues have not been used in the treatment of neovascular glaucoma because of suspicious lack of efficacy. This study aims at assessing the effect of travoprost on neovascular glaucoma.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2008

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 27, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 28, 2007

Completed
10 months until next milestone

Study Start

First participant enrolled

January 1, 2008

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
Last Updated

June 22, 2011

Status Verified

February 1, 2007

First QC Date

February 27, 2007

Last Update Submit

June 21, 2011

Conditions

Neovascular Glaucoma

Keywords

Neovascular glaucomaTravoprost

Outcome Measures

Primary Outcomes (1)

  • Intraocular pressure

Secondary Outcomes (1)

  • Inflammation

Interventions

TravoprostDRUG

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Neovascular glaucoma of known cause
  • Older than 18 years
  • Previously submitted to retinal photocoagulation
  • Under medical treatment to glaucoma

You may not qualify if:

  • Need of antiglaucomatous surgery
  • Previous ocular surgery in the last 6 months
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Federal University of São Paulo

São Paulo, São Paulo, 04023-900, Brazil

Location

MeSH Terms

Conditions

Glaucoma, Neovascular

Interventions

Travoprost

Condition Hierarchy (Ancestors)

GlaucomaOcular HypertensionEye Diseases

Intervention Hierarchy (Ancestors)

CloprostenolProstaglandins F, SyntheticProstaglandins, SyntheticProstaglandinsEicosanoidsFatty Acids, UnsaturatedFatty AcidsLipidsAutacoidsInflammation MediatorsBiological Factors

Study Officials

  • Luiz A Melo Jr, MD

    Federal University of São Paulo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 27, 2007

First Posted

February 28, 2007

Study Start

January 1, 2008

Study Completion

December 1, 2008

Last Updated

June 22, 2011

Record last verified: 2007-02

Locations

BR(1)