NCT02260219

Brief Summary

Objective: Prospectively evaluate the safety and efficacy of the Ahmed Glaucoma Drainage Device, model M4 compared with the model S2. Method: Mexican patients with Neovascular Glaucoma will be randomly included for each group (M4 and S2). They will be operated using conventional techniques and creating a sub-episcleral tunnel to place the valve's tube in the anterior chamber. They will be monitoring for one year and the results will be evaluated with respect to a postoperative reduction in pressure, changes in visual acuity, the need for drugs and complications, in addition to the demographic characteristics of each group.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2012

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2013

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

July 17, 2014

Completed
3 months until next milestone

First Posted

Study publicly available on registry

October 9, 2014

Completed
Last Updated

May 30, 2024

Status Verified

May 1, 2024

Enrollment Period

1.1 years

First QC Date

July 17, 2014

Last Update Submit

May 29, 2024

Conditions

Keywords

Ahmed implantNeovascular GlaucomaIntraocular pressure

Outcome Measures

Primary Outcomes (1)

  • Number of participants with adverse effects

    1 year

Secondary Outcomes (1)

  • Intraocular pressure

    1 year

Study Arms (2)

S2

ACTIVE COMPARATOR

Surgically Implant an Ahmed Glaucoma Drainage Device Model S2 in Neovascular Glaucoma Patients and evaluate the IOP evolution, complications and need for medication to control IOP

Procedure: Surgical Implant of Ahmed Glaucoma Drainage Device, model M4 and S2

M4

ACTIVE COMPARATOR

Surgically Implant an Ahmed Glaucoma Drainage Device Model M4 in Neovascular Glaucoma Patients and evaluate the IOP evolution, complications and need for medication to control IOP

Procedure: Surgical Implant of Ahmed Glaucoma Drainage Device, model M4 and S2

Interventions

Surgically Implant an Ahmed Glaucoma Drainage Device Models S2 and M4, evaluare IOP evolution, complications and need for medication to control IOP

M4S2

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with diagnosis of Neovascular glaucoma
  • High IOP despite topical treatment

You may not qualify if:

  • Pregnant women
  • Mental disorders
  • Previous glaucoma surgery
  • Patients older than 18 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Glaucoma, Neovascular

Interventions

Epinephrine

Condition Hierarchy (Ancestors)

GlaucomaOcular HypertensionEye Diseases

Intervention Hierarchy (Ancestors)

EthanolaminesAmino AlcoholsAlcoholsOrganic ChemicalsAminesBiogenic MonoaminesBiogenic AminesCatecholaminesCatecholsPhenolsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbons

Study Officials

  • Felix Gil-Carrasco, MD

    52 55 10841400

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 17, 2014

First Posted

October 9, 2014

Study Start

January 1, 2012

Primary Completion

February 1, 2013

Study Completion

February 1, 2013

Last Updated

May 30, 2024

Record last verified: 2024-05