Does Vnotes Salpingectomy Reduce Ovarian Reserve?

NCT07177144 | Completed

• 1 other identifier: Gaziosmanpasatrehmh
• Study Type: interventional
• Target: 46
• Locations: 1 country
• Sites: 1

Brief Summary

Comparison of Transvaginal Natural Orifice Transluminal Endoscopic Surgery and Conventional Laparoscopy in terms of their effects on ovarian reserve in Opportunistic Bilateral Salpingectomy for Permanent Female Sterilization

Conditions

Vnotes; Salpingectomy; Ovarian Reserve

Keywords

vnotes; salpingectomy; ovarian reserve

Outcome Measures

Primary Outcomes (1)

• measuring anti-millerian hormone level

  To evaluate the effect of two surgical methods on ovarian reserve by measuring serum anti-Müllerian hormone levels (ng/ml) before surgery and after salpingectomy.

  amh level (ng/ml) will be checked before the operation, and after 3 months, she will be called for control and measured again.

Secondary Outcomes (3)

• comparison of duration of surgery

  Perioperative

• Postoperative hospital stay duration

  Perioperative

• postoperative pain

  first hour after surgery

Study Arms (2)

vnotes salpingectomy performed

EXPERIMENTAL

group of women who underwent salpingectomy with the vnotes method for women who wanted to have their tubes removed for contraception

Other: anti müllerian hormone; Diagnostic Test: anti müllerian hormon

laparoscopic salpingectomy performed

ACTIVE COMPARATOR

group of women who underwent salpingectomy with the laparoscopic salpingectomy method for women who wanted to have their tubes removed for contraception

Other: anti müllerian hormone; Diagnostic Test: anti müllerian hormon

Interventions

anti müllerian hormone OTHER

participants were checked for amh levels preoperatively

laparoscopic salpingectomy performed; vnotes salpingectomy performed

anti müllerian hormon DIAGNOSTIC_TEST

participants were checked for amh levels at 3 months postoperatively.

laparoscopic salpingectomy performed; vnotes salpingectomy performed

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• to want to have your tubes removed, not to have undergone tubal and ovarian surgery before, not to use hormones and medications that can affect the level of sex hormones and its levels,

You may not qualify if:

• not being in the specified age range (18-45), having a history of tubal ligation, having tubal cancer

Sponsors & Collaborators

• Gaziosmanpasa Research and Education Hospital: lead

Study Sites (1)

Gaziosmanpaşa Education and Research Hospital

Istanbul, Turkey (Türkiye)

Location

Related Publications (1)

• Yassa M, Kaya C, Kalafat E, Tekin AB, Karakas S, Mutlu MA, Birol P, Tug N. The Comparison of Transvaginal Natural Orifice Transluminal Endoscopic Surgery and Conventional Laparoscopy in Opportunistic Bilateral Salpingectomy for Permanent Female Sterilization. J Minim Invasive Gynecol. 2022 Feb;29(2):257-264.e1. doi: 10.1016/j.jmig.2021.08.009. Epub 2021 Aug 16.

  PMID: 34411729 RESULT

MeSH Terms

Interventions

Anti-Mullerian Hormone

Intervention Hierarchy (Ancestors)

Testicular Hormones; Gonadal Hormones; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Glycoproteins; Glycoconjugates; Carbohydrates; Proteins; Amino Acids, Peptides, and Proteins

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor of gynecology and obstetrics

Study Record Dates

• First Submitted: August 18, 2025
• First Posted: September 16, 2025
• Study Start: June 19, 2025
• Primary Completion: November 17, 2025
• Study Completion: November 17, 2025
• Last Updated: November 19, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)