Morphological Changes of Upper Trapezius Muscle After Physotherapy in Oral Cancer

NCT07166575 | Not Yet Recruiting

• 1 other identifier: 202508084RINA
• Study Type: observational
• Target: 10
• Locations: 0 countries
• Sites: N/A

Brief Summary

The study aims to evaluate the morphological changes of upper trapezius muscle, using B-mode ultrasonography, in patients with oral cancer undergone neck dissection and physiotherapy. It also investigates the relationship between morphological changes and shoulder active range of motion in abduction. Furthermore , the study assesses the potential of B-mode ultrasonography as an objective tool for monitoring outcomes of the rehabilitation in this population.

Conditions

Oral Cancer

Keywords

Ultrasonography; Upper Trapezius; Shoulder; Oral Cancer

Outcome Measures

Primary Outcomes (3)

• Cross-sectional area of upper trapezius muscle

  CSA of the upper trapezius muscle is measured via B-mode panoramic ultrasonography. Panoramic B-mode ultrasonography will be performed by placing the probe at the spinous process of the fourth cervical vertebra (C4) and moving it laterally toward the posterior margin of the sternocleidomastoid muscle.

  Pre-intervention, 8 weeks post-intervention

• Thickness of upper trapezius muscle

  Thickness of upper trapezius muscle is measured via B-mode ultrasonography. The ultrasound probe will be positioned at the midpoint between the spinous process of the seventh cervical vertebra (C7) and the acromion, aligned parallel to the muscle fibers.

  Pre-intervention, 8 weeks post-intervention

• Active range of motion in shoulder abduction

  AROM in shoulder abduction is measured by a goniometer, with the fulcrum positioned over the anterior aspect of the acromial process. The proximal arm is aligned parallel to the midline of the anterior aspect of the sternum, while the distal arm is aligned with the anterior midline of the humerus.

  Pre-intervention, 8 weeks post-intervention

Interventions

B-mode ultrasonography DIAGNOSTIC_TEST

Thickness and cross-sectional area of upper trapezius muscle

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A total of 10 newly diagnosed oral cancer patients who received neck dissection with scapular dyskinesis

You may qualify if:

• Newly diagnosed oral cancer patients with scapular dyskinesis, who have undergone neck dissections within 3 months
• Able to cooperate with assessments and physical therapy, and capable of understanding and signing the informed consent form.
• Age between 20 and 65 years.

You may not qualify if:

• Unable to effectively communicate.
• Diagnosed with conditions affecting motor function.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Related Publications (5)

• Carenfelt C, Eliasson K. Occurrence, duration and prognosis of unexpected accessory nerve paresis in radical neck dissection. Acta Otolaryngol. 1980 Nov-Dec;90(5-6):470-3. doi: 10.3109/00016488009131750.

  PMID: 7211339 BACKGROUND

• Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol. 2009 Apr-May;45(4-5):309-16. doi: 10.1016/j.oraloncology.2008.06.002. Epub 2008 Sep 18.

  PMID: 18804401 BACKGROUND

• van Wilgen CP, Dijkstra PU, van der Laan BF, Plukker JT, Roodenburg JL. Shoulder complaints after neck dissection; is the spinal accessory nerve involved? Br J Oral Maxillofac Surg. 2003 Feb;41(1):7-11. doi: 10.1016/s0266-4356(02)00288-7.

  PMID: 12576033 BACKGROUND

• Adigozali H, Shadmehr A, Ebrahimi E, Rezasoltani A, Naderi F. Ultrasonography for the assessment of the upper trapezius properties in healthy females: a reliability study. Muscles Ligaments Tendons J. 2016 May 19;6(1):167-72. doi: 10.11138/mltj/2016.6.1.167. eCollection 2016 Jan-Mar.

  PMID: 27331047 BACKGROUND

• Valera-Calero JA, Gallego-Sendarrubias G, Fernandez-de-Las-Penas C, Cleland JA, Ortega-Santiago R, Arias-Buria JL. Cross-sectional area of the cervical extensors assessed with panoramic ultrasound imaging: Preliminary data in healthy people. Musculoskelet Sci Pract. 2020 Dec;50:102257. doi: 10.1016/j.msksp.2020.102257. Epub 2020 Sep 11.

  PMID: 32947195 BACKGROUND

MeSH Terms

Conditions

Mouth Neoplasms

Condition Hierarchy (Ancestors)

Head and Neck Neoplasms; Neoplasms by Site; Neoplasms; Mouth Diseases; Stomatognathic Diseases

Study Officials

• Yueh-Hsia Chen, PhD

  National Taiwan University, College of Medicine

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Yueh-Hsia Chen, PhD

CONTACT

+886-2-33668133; yuehhsiachen@ntu.edu.tw

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 8 Weeks
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 2, 2025
• First Posted: September 10, 2025
• Study Start: September 15, 2025
• Primary Completion (Estimated): July 31, 2026
• Study Completion (Estimated): July 31, 2026
• Last Updated: September 10, 2025

Record last verified: 2025-08