The Role of microRNA-29b in the Oral Squamous Cell Carcinoma

NCT02009852 | Unknown DMC

• 1 other identifier: 201309076RIN
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The Role of microRNA-29b in the Oral Squamous Cell Carcinoma

Conditions

Oral Cancer

Keywords

microRNA-29b; Oral squamous cell carcinoma; migration; prognosis

Outcome Measures

Primary Outcomes (1)

• microRNA-29b

  3 years

Study Arms (1)

Oral cancer

Subjects who suffer from oral cancer. Subjects must: Should have a blood exam (20ml/each time) before the surgery and 3 months after the surgery. In the case the disease recurs after the surgery, subjects need to receive the surgery again and take another blood exam before the surgery and 3 months after the surgery. Before the surgery site staff must: Collect subjects' saliva once a day (in the morning before breakfast) for 3 consecutive days. Collect a 0.5x0.5Cm2 tissue sample of the tumor during the surgery.

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Medical center

You may qualify if:

• Cancer of the oral cavity.

You may not qualify if:

• pregnant woman
• refuse the surgery

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital research Ethics Committee

Taipei, 10048, Taiwan

Location

Related Publications (20)

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Biospecimen

Retention: SAMPLES WITH DNA

tissue, serum, saliva

MeSH Terms

Conditions

Mouth Neoplasms; Squamous Cell Carcinoma of Head and Neck

Condition Hierarchy (Ancestors)

Head and Neck Neoplasms; Neoplasms by Site; Neoplasms; Mouth Diseases; Stomatognathic Diseases; Carcinoma, Squamous Cell; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type

Study Officials

• Shin-Jung Cheng, DDS, MS, PhD

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Shin-Jung Cheng, DDS, MS, PhD

CONTACT

+886 2 29251733; sjcheng56@ntu.edu.tw

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Target Duration: 3 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 9, 2013
• First Posted: December 12, 2013
• Study Start: January 1, 2014
• Primary Completion: December 1, 2014
• Last Updated: December 12, 2013

Record last verified: 2013-12

Locations

TW (1)