AI Based Physiotherapy 3- and 9-Month Follow-Up in Oral Cancer Patients

NCT07237672 | Recruiting

• 1 other identifier: 202412109RIND
• Study Type: interventional
• Target: 65
• Locations: 1 country
• Sites: 1

Brief Summary

This follow-up clinical study aims to evaluate the sustained effects of two rehabilitation programs (AI-based physiotherapy vs. conventional physiotherapy) for oral cancer patients. Participants who completed the original intervention trial (ClinicalTrials.gov ID: 202411044RINC) will be assessed at 3 and 9 months post-intervention. Outcomes include mandibular mobility, shoulder joint range of motion, functional performance, quality of life, pain, and return-to-work status.

Conditions

Oral Cancer

Keywords

Artificial intelligence; Oral cancer; Maximum interincisal opening; Physical function; Prehabilitation; Physiotherapy

Outcome Measures

Primary Outcomes (2)

• Disabilities of the Arm, Shoulder, and Hand outcome questionnaire

  A total scale from 1 to 100. Higher scores indicate greater disability

  3 months, 9 months post-intervention

• EORTC QLQ-C30 questionnaire

  A total scale from 1 to 100. Higher scores indicate greater function

  3 months, 9 months post-intervention

Secondary Outcomes (1)

• Return-to-work status

  3 months, 9 months post-intervention

Study Arms (2)

Experimental group (Follow-up)

EXPERIMENTAL

Participants who originally received AI-based physiotherapy will undergo follow-up assessments at 3 and 9 months post-intervention.

Other: AI-based physiotherapy follow-up assessments

Control group (Follow-up)

ACTIVE COMPARATOR

Participants who originally received conventional physiotherapy will undergo follow-up assessments at 3 and 9 months post-intervention.

Other: conventional physiotherapy follow-up assessments

Interventions

AI-based physiotherapy follow-up assessments OTHER

AI-based physiotherapy and 3 and 9 months follow-up assessments

Experimental group (Follow-up)

conventional physiotherapy follow-up assessments OTHER

conventional physiotherapy and 3 and 9 months follow-up assessments

Control group (Follow-up)

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Participants who completed the intervention phase of the previous trial (202411044RINC)
• Age 20-65 years
• Able to attend follow-up assessments at 3 and 9 months

You may not qualify if:

• Withdrawal from the original trial
• Cancer recurrence or new cancer-related treatment interfering with functional assessment
• Unable to communicate or comply with follow-up visits

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan

Taipei, 100, Taiwan

RECRUITING

Related Publications (25)

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MeSH Terms

Conditions

Mouth Neoplasms

Condition Hierarchy (Ancestors)

Head and Neck Neoplasms; Neoplasms by Site; Neoplasms; Mouth Diseases; Stomatognathic Diseases

Study Officials

• Yueh-Hsia Chen, Ph.D.

  National Taiwan University, College of Medicine

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Yueh-Hsia Chen, Ph.D.

CONTACT

+886-2-33668133; yuehhsiachen@ntu.edu.tw

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Masking Details: Follow-up only, no new intervention
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 2, 2025
• First Posted: November 20, 2025
• Study Start: December 6, 2025
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: December 16, 2025

Record last verified: 2025-10

Locations

TW (1)