Lung Ultrasound Versus Inferior Vena Cava Collapsibility Index for Early Prediction of Volume Overload During Transurethral Resection of Prostate

NCT07164638 | Enrolling By Invitation

• 1 other identifier: 36264MS733/11/24
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to compare between accuracy of lung US and IVC CI for early prediction of volume overload during TURP. Primary outcome: The incidence of volume overload during transurethral resection of prostate.

Conditions

Lung Ultrasound Score; Transurethral Resection (TUR) Syndrome; Prostate

Keywords

Lung Ultrasound; Inferior Vena Cava Collapsibility Index; Overload during Transurethral Resection; Prostate

Outcome Measures

Primary Outcomes (1)

• incidence of volume overload

  2 HOURS

Secondary Outcomes (1)

• ABG (PaO2 and O2 saturation)

  2 HOURS

Study Arms (2)

Group I: lung ultrasound (LUS) group

EXPERIMENTAL

Serial lung ultrasound will be performed to patients enrolled in this study before the beginning of the surgery, every 15 minutes in the first 30 minutes, and then every 30 minutes for the rest of the operation.

Procedure: lung ultrasound (LUS)

Group II: IVC collapsibility index group

EXPERIMENTAL

Serial assessment of IVC collapsibility will be used as a monitoring of volume overload in patients enrolled in this study.

Procedure: IVC collapsibility index

Interventions

lung ultrasound (LUS) PROCEDURE

Serial lung ultrasound will be performed to patients enrolled in this study before the beginning of the surgery, every 15 minutes in the first 30 minutes, and then every 30 minutes for the rest of the operation.lung ultrasound will be used as a tool for monitoring of EVLW to identify early the subclinical pulmonary edema and ensure timely and correct diagnosis and appropriate management.

Group I: lung ultrasound (LUS) group

IVC collapsibility index PROCEDURE

Serial assessment of IVC collapsibility will be used as a monitoring of volume overload in patients enrolled in this study. Basal IVC scanning using ultrasound will be performed before the start of the operation and serial IVC scanning will be done during the procedure every 15 minutes in the first 30 minutes, and then every 30 minutes for the rest of the operation.

Group II: IVC collapsibility index group

Eligibility Criteria

• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Male patient
• American Society of Anesthesiologists classification II-III
• scheduled for Transurethral resection of the prostate syndrome under spinal anesthesia.

You may not qualify if:

• Patient refusal.
• Uncooperative patients.
• Patients with major respiratory, cardiac, renal or hepatic disorders.
• Patients whose ultrasound did not clearly show the inferior vena cava as (morbidly obese patients or patients with moderate to marked ascites).
• Patients who have contraindications to spinal anesthesia (neurological disease, severe hypotension, coagulopathy, low fixed cardiac output).

Sponsors & Collaborators

• Tanta University: lead

Study Sites (1)

Tanta University

Tanta, Egypt

Location

MeSH Terms

Conditions

Syndrome

Condition Hierarchy (Ancestors)

Disease; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Shereen El-Sabry

  Tanta University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: September 2, 2025
• First Posted: September 10, 2025
• Study Start: October 30, 2024
• Primary Completion: October 30, 2025
• Study Completion: October 30, 2025
• Last Updated: September 10, 2025

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)