Effects of Multiple Interventions on Under-Five Diarrhea

NCT07158632 | Not Yet Recruiting

• 1 other identifier: JUIH/IRB/0509/25
• Study Type: interventional
• Target: 840
• Locations: 1 country
• Sites: 1

Brief Summary

Diarrhea is the leading cause of death, especially in developed nations. Though there are effective interventions, diarrhea remains the leading cause of death among children in Ethiopia

Conditions

Diarrheal Diseases

Keywords

central Ethiopia, Diarrhea, Ethiopia, Multiple Interventions

Outcome Measures

Primary Outcomes (1)

• Incidence of diarrhea among under-five children

  At baseline and to four-month follow-up

Secondary Outcomes (1)

• Adherence of interventions

  Up to four-month follow-up

Study Arms (4)

handwashing education only arm

EXPERIMENTAL

Arm A: This arm receives handwashing education.

Behavioral: handwashing education

water chlorination only arm

EXPERIMENTAL

Arm B: This arm receives household water chlorination

Behavioral: water chlorination

combined hand washing and water chlorination arm

EXPERIMENTAL

Arm C: This arm receives both handwashing education and water chlorination.

Behavioral: combined intervention

No intervention arm

NO INTERVENTION

This arm have not receive any intervention

Interventions

handwashing education BEHAVIORAL

Arm A: This arm receive handwashing education using social and behavioral change communication

handwashing education only arm

water chlorination BEHAVIORAL

Arm B: This arm receives water chlorination intervention

water chlorination only arm

combined intervention BEHAVIORAL

Arm C: This arm receives combined handwashing and water chlorination intervention

combined hand washing and water chlorination arm

Eligibility Criteria

• Age: 6 Months - 59 Months
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may not qualify if:

• severely ill mother, households that receive treated water

Sponsors & Collaborators

• Jimma University: lead

Study Sites (1)

Butajira Health Center

Butajīra, Ethiopia

Location

Related Publications (1)

• Breastfeeding and protection against diarrhea: an integrative review of literature Aleitamento materno e proteção contra diarreia: revisão integrativa da literatura Floriacy Stabnow Santos1 , Felipe César Stabnow Santos2 Adriana Moraes Leite1 , Leonardo Hunaldo dos Santos3 , Débora Falleiros de Mello1

  BACKGROUND

MeSH Terms

Conditions

Diarrhea

Condition Hierarchy (Ancestors)

Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Melaku Tesfaye PhD Candidate, MPH

CONTACT

+251916141771; tesfayemelaku96@gmail.com=

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD Candidate

Model Details: The study contains four arms; these are handwashing education arm, water chlorination arm, combination arm, and control arm

Study Record Dates

• First Submitted: August 22, 2025
• First Posted: September 8, 2025
• Study Start: September 8, 2025
• Primary Completion: December 10, 2025
• Study Completion: December 24, 2025
• Last Updated: September 9, 2025

Record last verified: 2025-09

Locations

ET (1)