NCT00929838

Brief Summary

Blacks or African Americans have greater risk of and are more likely to die from type 2 diabetes (T2DM). Major barriers to effective diabetes care for Blacks include poor diabetes knowledge, self-management skills, empowerment, and perceived control. Few prior studies have tested interventions to address these barriers in combination, especially among Blacks who have the greatest burden of diabetes related complications. This study provides a unique opportunity to address this gap in the literature by testing the efficacy of separate and combined telephone-delivered, diabetes knowledge and motivation/behavioral skills training intervention in high risk Blacks with poorly controlled T2DM. The findings of this study, if successful, will provide new information on how to improve quality of care for diabetes in ethnic minorities and reduce the disproportionate burden of diabetes complications and deaths in this population.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
256

participants targeted

Target at P75+ for not_applicable diabetes-mellitus-type-2

Timeline
Completed

Started Aug 2008

Longer than P75 for not_applicable diabetes-mellitus-type-2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2008

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

June 29, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

June 30, 2009

Completed
6.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2016

Completed
2.9 years until next milestone

Results Posted

Study results publicly available

April 10, 2019

Completed
Last Updated

July 12, 2024

Status Verified

July 1, 2024

Enrollment Period

7.8 years

First QC Date

June 29, 2009

Results QC Date

May 14, 2018

Last Update Submit

July 10, 2024

Conditions

Keywords

Diabetes Mellitus, Type 2Diabetes Mellitus, Adult-OnsetDiabetes Mellitus, Non-Insulin-DependentAfrican AmericansBlacksRandomized Controlled TrialControlled Clinical TrialBehavioral ResearchBehavioral Medicine

Outcome Measures

Primary Outcomes (1)

  • Hemoglobin A1c (HbA1c) at 12 Months Post Randomization

    12-months post randomization

Study Arms (4)

Diabetes Knowledge/Information Arm

EXPERIMENTAL

Subjects randomized to the diabetes knowledge/information arm will complete 12 diabetes education modules over a 12-week period. The educational materials were developed based on guidelines for diabetes education by the American Diabetes Association. The content is based on the principles of the Adult Learning Theory. The information is designed to be relevant, person centered, and presented in a non-threatening manner. The modules are designed to be delivered via telephone in 10-15 minutes, so that the maximum contact time per telephone call including introduction and closing would not exceed 30 minutes.

Behavioral: Diabetes Knowledge/Information

Motivation/Behavioral Skills Arm

EXPERIMENTAL

The motivation/behavioral skills intervention consists of patient activation (list of 5 questions to ask their provider at every visit and training on how to ask the questions), patient empowerment (diabetes responsibility contracts, personal goals, and flow charts for patients to record lab results/medications and training on how to use the empowerment tools), and behavioral skills training delivered via telephone lasting 30 minutes every week for 12 weeks. The behavioral skills training will be focused on 4 behaviors - physical activity, diet, medication adherence, and glucose self-monitoring. Guided by subjects' current problem areas and preferences, subjects will be asked to choose 1 of 4 behaviors to focus on every 3 weeks (4 behaviors over 12 weeks).

Behavioral: Motivation/Behavioral Skills

Combined Intervention Arm

EXPERIMENTAL

The combined intervention group will receive weekly telephone-delivered diabetes knowledge/information, patient activation (list of 5 questions to ask their provider at every visit and training on how to ask the questions), patient empowerment (diabetes responsibility contracts, personal goals, and flow charts for patients to record lab results/medications and training on how to use the empowerment tools), and behavioral skills training delivered via telephone. The behavioral skills training will be focused on 4 behaviors and guided by subjects' current problem areas and preferences, subjects will be asked to choose 1 of 4 behaviors to focus on every 3 weeks. The combined intervention group telephone sessions will last for 30 minutes.

Behavioral: Combined Intervention

Usual Care Arm

SHAM COMPARATOR

The usual care group will receive weekly telephone-delivered general health education lasting 30 minutes for 12 weeks to control for attention. Patients in the usual care group will continue to receive any usual diabetes education provided by the clinic staff; however, they will not receive targeted diabetes knowledge/information, activation, empowerment, or behavioral skills training.

Behavioral: Usual Care

Interventions

This group will receive telephone-delivered diabetes knowledge/information lasting 30 minutes for 12 weeks.

Diabetes Knowledge/Information Arm

This intervention consists of patient activation, patient empowerment, and behavioral skills training delivered via telephone lasting 30 minutes every week for 12 weeks.

Motivation/Behavioral Skills Arm

This group will receive all components of the diabetes knowledge/information and the motivation/behavioral skills interventions via telephone lasting 30 minutes every week for 12 weeks.

Combined Intervention Arm
Usual CareBEHAVIORAL

This group will receive telephone-delivered general health education lasting 30 minutes for 12 weeks to control for attention and content.

Usual Care Arm

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \) Age ≥18 years
  • \) Clinical diagnosis of T2DM and HbA1c ≥9% at the screening visit
  • \) Self-identified as Black or African American
  • \) Subject must be taking at least one oral medication for diabetes, hypertension, or hyperlipidemia and must be willing to use the MEMS cap and bottle for 12 months
  • \) Subjects must be able to communicate in English
  • \) Subjects must have access to a telephone (landline or cell phone) for the 12 week intervention period

You may not qualify if:

  • \) Mental confusion on interview suggesting significant dementia
  • \) Participation in other diabetes clinical trials
  • \) Alcohol or drug abuse/dependency
  • \) Active psychosis or acute mental disorder
  • \) Life expectancy \<6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical University of South Carolina

Charleston, South Carolina, 29425, United States

Location

Related Publications (2)

  • Egede LE, Strom JL, Durkalski VL, Mauldin PD, Moran WP. Rationale and design: telephone-delivered behavioral skills interventions for Blacks with Type 2 diabetes. Trials. 2010 Mar 29;11:35. doi: 10.1186/1745-6215-11-35.

    PMID: 20350322BACKGROUND
  • Egede LE, Williams JS, Voronca DC, Gebregziabher M, Lynch CP. Telephone-Delivered Behavioral Skills Intervention for African American Adults with Type 2 Diabetes: A Randomized Controlled Trial. J Gen Intern Med. 2017 Jul;32(7):775-782. doi: 10.1007/s11606-017-4023-0. Epub 2017 Mar 23.

Related Links

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Interventions

Information Motivation Behavioral Skills Model

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Models, PsychologicalModels, TheoreticalInvestigative Techniques

Results Point of Contact

Title
Jennifer Campbell
Organization
Medical College of Wisconsin

Study Officials

  • Leonard E Egede, MD, MS

    Medical University of South Carolina (MUSC)

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor & Chair, Department of Medicine

Study Record Dates

First Submitted

June 29, 2009

First Posted

June 30, 2009

Study Start

August 1, 2008

Primary Completion

June 1, 2016

Study Completion

June 1, 2016

Last Updated

July 12, 2024

Results First Posted

April 10, 2019

Record last verified: 2024-07

Locations