NCT07156292

Brief Summary

Infective endocarditis has long been one of the significant diseases causing death and disability worldwide. Its incidence has shown an increasing trend over the past few decades. Moreover, there seems to be significant variation in prevalence and epidemiology in different geographic regions and countries. This study aims to understand the trends and changes in the epidemiology of infective endocarditis in Taiwan from the 2006s to the present. Through a retrospective database analysis using the "Taiwan Healthcare System Integration Database," the goal is to improve the prognosis of infective endocarditis treatment in Taiwan.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
2,247

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2023

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 8, 2023

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

April 28, 2025

Completed
4 months until next milestone

First Posted

Study publicly available on registry

September 5, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

September 5, 2025

Status Verified

April 1, 2025

Enrollment Period

2.1 years

First QC Date

April 28, 2025

Last Update Submit

September 1, 2025

Conditions

Keywords

Infective endocarditisepidemiology2006 to 2022

Outcome Measures

Primary Outcomes (1)

  • Recent epidemiological trends and changes in infective endocarditis in Taiwan over the past decades

    2006 to 2022

Interventions

Observational study, not interventional

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022

You may qualify if:

  • Patients who were discharged from hospital or received an emergency diagnosis of infective endocarditis between January 1, 2006 and December 31, 2022

You may not qualify if:

  • Patients without infective endocarditis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NTUH

Taipei, Taiwan

Location

MeSH Terms

Conditions

Endocarditis

Interventions

Observation

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

MethodsInvestigative Techniques

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
WANG-HUEI SHENG

Study Record Dates

First Submitted

April 28, 2025

First Posted

September 5, 2025

Study Start

November 8, 2023

Primary Completion

December 31, 2025

Study Completion

December 31, 2025

Last Updated

September 5, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will share

local epidemiology in order

Shared Documents
STUDY PROTOCOL

Locations