NCT07142824

Brief Summary

The aim of this study is to evaluate the use of tilapia fish skin as a healing dressing in burn patients and its clinical outcome and compare it with regular dressing.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2025

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 13, 2025

Completed
14 days until next milestone

First Posted

Study publicly available on registry

August 27, 2025

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2026

Completed
Last Updated

August 27, 2025

Status Verified

August 1, 2025

Enrollment Period

6 months

First QC Date

August 13, 2025

Last Update Submit

August 25, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Effect of burn dressing using Tilapia-Fish Skin versus regular dressing on wound healing

    Time of healing process

    3 weeks after regular dressing

Study Arms (2)

burn dressing using Tilapia-Fish Skin

ACTIVE COMPARATOR

we use tilapia fish skin as a healing dressing in burn patients

Procedure: burn dressing using Tilapia-Fish Skin

burn dressing using regular dressing

ACTIVE COMPARATOR

we use regular dressing in burn patients

Procedure: burn dressing using regular dressing

Interventions

we use tilapia fish skin as a healing dressing in burn patients

burn dressing using Tilapia-Fish Skin

we use regular dressing in burn patients

burn dressing using regular dressing

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with second or third-degree burns.

You may not qualify if:

  • Patients with first-degree burns.
  • Patients with burn injuries complicated by sepsis.
  • Patients who received prior wound healing agents.
  • Elderly patients or those with chronic diseases such as diabetes mellitus.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sohag University Hospital

Sohag, Egypt

RECRUITING

Related Publications (3)

  • Dhivya S, Padma VV, Santhini E. Wound dressings - a review. Biomedicine (Taipei). 2015 Dec;5(4):22. doi: 10.7603/s40681-015-0022-9. Epub 2015 Nov 28.

    PMID: 26615539BACKGROUND
  • Hu Z, Yang P, Zhou C, Li S, Hong P. Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation. Mar Drugs. 2017 Mar 30;15(4):102. doi: 10.3390/md15040102.

    PMID: 28358307BACKGROUND
  • Ibrahim A, Soliman M, Kotb S, Ali MM. Evaluation of fish skin as a biological dressing for metacarpal wounds in donkeys. BMC Vet Res. 2020 Dec 3;16(1):472. doi: 10.1186/s12917-020-02693-w.

    PMID: 33272259BACKGROUND

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Central Study Contacts

Osama M Mohamed, Resident

CONTACT

Gamal Y Elsayed, Professor

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident, Department of Plastic Surgery, Faculty of Medicine, Sohag University

Study Record Dates

First Submitted

August 13, 2025

First Posted

August 27, 2025

Study Start

July 1, 2025

Primary Completion

January 1, 2026

Study Completion

January 1, 2026

Last Updated

August 27, 2025

Record last verified: 2025-08

Locations