Response of Liver to 12 Weeks of Resistance Band Training Program in Burned Patients.

NCT06067711 | Completed

• 1 other identifier: P.T.REC/012/004652
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Serum concentrations of alanine transaminase (ALT) and aspartate transaminase (AST) significantly increased immediately upon burn trauma and remained significantly elevated for about three years. Resistance training has been shown to reduce the risk of insulin resistance, aminotransfer¬ase levels, dyslipidemia and impaired fasting glucose and can be beneficial for glucose-lipid metabolism.

Conditions

Burns

Keywords

Plasma elevated liver enzymes

Outcome Measures

Primary Outcomes (1)

• Concentration of Alanine transaminase (ALT) and Aspartate transaminase(AST) in blood plasma.

  Liver enzymes

  Three months

Study Arms (2)

Resistance band training group:

EXPERIMENTAL

This group includes 30 burned patients who will receive resistance training program for 12 weeks (3times/week) using resistance band in addition to their traditional physical therapy program and medical treatment.

Device: resistance band

Control group:

NO INTERVENTION

This group includes 30 burned patients who will receive only their traditional physical therapy program and medical treatment.

Interventions

resistance band DEVICE

The program will consist of six exercises: triceps press, biceps curl, lat pull down, leg press, leg extension and sit-ups using resistance band.

Resistance band training group:

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• The subject selection will be according to the following criteria:
• Age range between 20-45 years.
• Male and female patients will participate in the study.
• All patients have burn with BBSA about 30% to 50%.
• All patients enrolled to the study will have their informed consent.

You may not qualify if:

• The potential participants will be excluded if they meet one of the following criteria:
• Cardiac diseases.
• Burn of sole of foot.
• Exposed hand or foot tendons.
• Upper or Lower limb amputation.
• History of liver diseases.
• Body mass index (BMI=kg/cm2)\<30%.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical therapy, Cairo University

Giza, 3387722, Egypt

Location

MeSH Terms

Conditions

Burns

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• A G Elsayed, PHD

  Cairo University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of physical therapy of surgery

Model Details: Resistance training will be performed during 12-weeks for 3 sessions/week on non-consecutive days. The program will consist of six exercises: triceps press, biceps curl, lat pull down, leg press, leg extension and sit-ups using resistance band. Each session will last approximately 45 minutes and consist of a 5-minute warm-up with stretching following by resistance training that will be done as a cir¬cuit, ending with 5-minute cool down. The 1 repetition maximum (1RM) is measured at baseline and follow¬ing the intervention.

Study Record Dates

• First Submitted: September 28, 2023
• First Posted: October 5, 2023
• Study Start: November 19, 2023
• Primary Completion: January 10, 2024
• Study Completion: March 30, 2024
• Last Updated: August 11, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)