Comparative Effect of Box Breathing And Buteyko Breathing on Pulmonary Functions in Asthma

NCT07140458 | Completed

• 1 other identifier: REC/RCR & AHS/24/0325 Ezaz
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to evaluate the Effectiveness of Box Breathing Technique and Buteyko breathing techniques in patients with Asthma, using both Clinical Pulmonary tests as well as Patient reported outcomes.

Conditions

Asthma (Diagnosis); Breathing Exercises

Keywords

Asthma; Breathing Exercise; Buteyko Breathing; Box Breathing; Pulmonary Function tests

Outcome Measures

Primary Outcomes (3)

• Lung Function tests (FVC)

  Changes from Baseline, Lung function tests measure how well the lungs take in, hold, and move air, as well as how efficiently they transfer oxygen into the blood. These tests help diagnose and monitor respiratory diseases like asthma, COPD, pulmonary fibrosis, and restrictive lung diseases. Tets measures are compared against Normal value i.e: FVC ≥80%.

  through study completion, approximately 8 weeks

• Lung Function Test (FEV¹)

  Changes from Baseline, Lung function tests measure how well the lungs take in, hold, and move air, as well as how efficiently they transfer oxygen into the blood. These tests help diagnose and monitor respiratory diseases like asthma, COPD, pulmonary fibrosis, and restrictive lung diseases. Test measures are compared against Normal value i.e: FEV¹ ≥80%.

  through study completion, approximately 8 weeks

• Lung Function test (FEV₁/FVC ratio)

  Changes from Baseline, Lung function tests measure how well the lungs take in, hold, and move air, as well as how efficiently they transfer oxygen into the blood. These tests help diagnose and monitor respiratory diseases like asthma, COPD, pulmonary fibrosis, and restrictive lung diseases. Test measures are compared against Normal value i.e: FEV₁/FVC ≥0.7.

  through study completion, approximately 8 weeks

Secondary Outcomes (2)

• Modified Borg Dyspnea Scale

  through study completion, approximately 8 weeks

• Mcgill quality of life questionnaire

  through study completion, approximately 8 weeks

Study Arms (2)

Buteyko Breathing

EXPERIMENTAL

Using Buteyko Breathing as primary intervention in addition to standard Asthma therapy.

Other: Buteyko Breathing

Box Breathing Technique

EXPERIMENTAL

Using Buteyko Breathing as primary intervention in addition to standard Asthma therapy.

Other: Box breathing

Interventions

Buteyko Breathing OTHER

Buteyko Breathing is a technique focusing on controlled, reduced breathing to improve oxygen uptake and reduce hyperventilation-related symptoms using Air hunger. Procedure:- After gaining proper relaxation: 1. Exhale slowly, and then hold that breath. 2. Use the index finger and thumb to plug the nose. 3. Hold that breath until there is an urge to breathe, and then inhale. 4. Breathe normally for at least 10 seconds. 5. Repeat several times.

Buteyko Breathing

Box breathing OTHER

Box Breathing (4-4-4-4 Technique) - Box Breathing exercises boosts lung function by optimizing oxygen flow and activating relaxation responses.Each exercise Sessions included 20 cycles of Box Breathing. The procedure of the box breathing cycle includes: 1. inhale for 4 seconds 2. Hold the breath for 4 seconds 3. Exhale for 4 seconds 4. Hold the breath for 4 seconds, and repeat.

Box Breathing Technique

Eligibility Criteria

• Age: 25 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Subjects with bronchial asthma for more than one year
• Subjects who are on regular treatment (both inhalers and medication).
• Subjects who are conscious and cooperative.

You may not qualify if:

• Subject with recent abdominal, thoracic surgery.
• Subject with any Disability; Physical or Mental.
• Subjects who have other chronic respiratory diseases, new or current smoker, and had respiratory tract infection.

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Islam center and Teaching Hospital

Sialkot, Punjab Province, 51310, Pakistan

Location

Related Publications (41)

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Related Links

• Global Strategy for Asthma Management and Prevention. \[Online Web Data\]. 2023

MeSH Terms

Conditions

Asthma; Disease

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Qurat ul Ain, Masters

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 14, 2025
• First Posted: August 24, 2025
• Study Start: December 17, 2024
• Primary Completion: February 14, 2025
• Study Completion: July 2, 2025
• Last Updated: August 24, 2025

Record last verified: 2025-08

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)