NCT07106086

Brief Summary

The objective of this study will be to determine the combine effect of scapulothoracic mobilization with Buteyko breathing on pulmonary parameters functional capacity and balance among COPD patient.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable chronic-obstructive-pulmonary-disease

Timeline
Completed

Started Jul 2024

Shorter than P25 for not_applicable chronic-obstructive-pulmonary-disease

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 20, 2024

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 20, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2024

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

July 28, 2025

Completed
9 days until next milestone

First Posted

Study publicly available on registry

August 6, 2025

Completed
Last Updated

August 6, 2025

Status Verified

August 1, 2025

Enrollment Period

4 months

First QC Date

July 28, 2025

Last Update Submit

August 2, 2025

Conditions

Keywords

BalanceBreathingCOPDFunctional CapacityMobilization

Outcome Measures

Primary Outcomes (3)

  • Oxygen Saturation

    Oxygen saturation is measured by Pulse oximeter The gold standard for measuring arterial blood oxygen saturation (SaO₂) requires arterial blood sampling, but pulse oximetry provides a non-invasive estimate (SpO₂) widely used to detect hypoxemia.

    Pre and 2 week Post intervention

  • Functional capacity

    Functional Capacity is measured by 6- minute walk test. The 6-minute walk test (6MWT) is a well-known tool to measure ability to walk and endurance in the sub-maximal condition. The 6MWT is a exercise test that involves measuring the distance walked over a span of 6 minutes. Participants were encouraged to walk on a straight, flat surface as fast as possible for 6 minutes on a marked course, with pauses as necessary.

    Pre and 2 week post intervention

  • Balance

    The Balance is measured by Single leg stance test. Single Leg Stance (SLS). The SLS is a simple balance test where the participant stands on one leg for as long as possible (up to 60 seconds) with hands on hips. The test is performed first with eyes open, then with eyes closed. Longer duration indicates better balance. The SLS has demonstrated excellent reliability in individuals with COPD as well as in community-dwelling older adults.

    Pre and 2 week post intervention

Secondary Outcomes (2)

  • Respiratory rate

    Pre and Post 2 week intervention

  • Heart rate

    Pre and Post 2 week intervention

Study Arms (2)

Scapulothoracic mobilization with buteyko breathing

EXPERIMENTAL

Scapulothoracic mobilization with buteyko breathing

Other: Scapulothoracic mobilizationOther: Buteyko breathing

Buteyko breathing

ACTIVE COMPARATOR

buteyko breathing

Other: Buteyko breathing

Interventions

Scapulothoracic Mobilization and Buteyko Breathing Technique: Subjects lay supine with arms crossed, hands on opposite scapulae. The interventionist stabilized elbows and applied pressure to shoulders, with one hand on the spine using a loose fist to mobilize vertebrae. Various spinal motions-rotation, flexion, lateral flexion, and translation-were assessed. In a lateral position, the subject bent both knees and placed the upper arm on a cushion. The interventionist stood close, placing fingers under the scapula's medial border.

Scapulothoracic mobilization with buteyko breathing

Buteyko Breathing: Subjects sat upright, relaxed respiratory muscles, and breathed gently through the nose. The sequence included calm nasal inhalation and exhalation using the diaphragm, followed by shallow inhalation and slow exhalation. A brief post-exhalation breath hold was added. The cycle was repeated for several minutes.

Buteyko breathingScapulothoracic mobilization with buteyko breathing

Eligibility Criteria

Age40 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinically Diagnosed COPD is confirmed by diagnostic criteria of COPD (forced expiratory volume in 1 second \[FEV1\] \<80% predicted, FEV1/forced vital capacity \[FVC\] \<0.7 predicted) according to the international guideline and the ability to provide inform consent.
  • Patients with Resting Respiratory Rate \>\_ 24

You may not qualify if:

  • Patients diagnosed with a primary pulmonary vascular disease
  • Patients diagnosed with severe psychiatric disorders and cognitive dysfunction
  • Patients diagnosed severe auditory/visual impairments
  • Patients diagnosed Musculoskeletal, Rheumatic ,Cardiac/Neurological disorder and Malignancies
  • Patients diagnosed with skin, peripheral vascular disorder excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Arif Memorial Teaching Hospital

Lahore, Punjab Province, Pakistan

Location

Related Publications (6)

  • Jarhyan P, Hutchinson A, Khaw D, Prabhakaran D, Mohan S. Prevalence of chronic obstructive pulmonary disease and chronic bronchitis in eight countries: a systematic review and meta-analysis. Bull World Health Organ. 2022 Mar 1;100(3):216-230. doi: 10.2471/BLT.21.286870. Epub 2022 Jan 19.

    PMID: 35261410BACKGROUND
  • Gore S, Blackwood J, Ziccardi T. Associations Between Cognitive Function, Balance, and Gait Speed in Community-Dwelling Older Adults with COPD. J Geriatr Phys Ther. 2023 Jan-Mar 01;46(1):46-52. doi: 10.1519/JPT.0000000000000323. Epub 2021 Jul 29.

    PMID: 34334706BACKGROUND
  • Chen Y, Li P, Wang J, Wu W, Liu X. Assessments and Targeted Rehabilitation Therapies for Diaphragmatic Dysfunction in Patients with Chronic Obstructive Pulmonary Disease: A Narrative Review. Int J Chron Obstruct Pulmon Dis. 2022 Mar 3;17:457-473. doi: 10.2147/COPD.S338583. eCollection 2022.

    PMID: 35273448BACKGROUND
  • Berriet AC, Beaumont M, Peran L, Le Ber C, Couturaud F. Effects of pulmonary rehabilitation on fear of falling in Chronic Obstructive Pulmonary Disease (COPD) patients: An observational study. Respir Med Res. 2022 Nov;82:100932. doi: 10.1016/j.resmer.2022.100932. Epub 2022 Jun 12.

    PMID: 35878569BACKGROUND
  • Alqahtani JS. Prevalence, incidence, morbidity and mortality rates of COPD in Saudi Arabia: Trends in burden of COPD from 1990 to 2019. PLoS One. 2022 May 19;17(5):e0268772. doi: 10.1371/journal.pone.0268772. eCollection 2022.

    PMID: 35588429BACKGROUND
  • Agusti A, Celli BR, Criner GJ, Halpin D, Anzueto A, Barnes P, Bourbeau J, Han MK, Martinez FJ, Montes de Oca M, Mortimer K, Papi A, Pavord I, Roche N, Salvi S, Sin DD, Singh D, Stockley R, Lopez Varela MV, Wedzicha JA, Vogelmeier CF. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Eur Respir J. 2023 Apr 1;61(4):2300239. doi: 10.1183/13993003.00239-2023. Print 2023 Apr.

    PMID: 36858443BACKGROUND

MeSH Terms

Conditions

Pulmonary Disease, Chronic ObstructiveRespiratory Aspiration

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsRespiration Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Physiotherapist

Study Record Dates

First Submitted

July 28, 2025

First Posted

August 6, 2025

Study Start

July 20, 2024

Primary Completion

November 20, 2024

Study Completion

December 30, 2024

Last Updated

August 6, 2025

Record last verified: 2025-08

Locations