Breathing Exercises on Lung Function

NCT06472167 | Recruiting DMC

• 1 other identifier: R.24.05.2638
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.

Conditions

Breathing Exercises

Keywords

Breathing exercises; lung function; Chronic airway diseases

Outcome Measures

Primary Outcomes (2)

• Impact of breathing exercises on Forced expiratory volume on first second (FEV1) in liter

  Effect of Breathing exercises on lung function using spirometry

  6 months

• Impact of breathing exercises on Forced vital capacity (FVC) in liter

  Effect of Breathing exercises on lung function using spirometry

  6 months

Study Arms (2)

Chronic airway diseases treated by medication

NO INTERVENTION

Chronic airway diseases treated by medication without breathing exercises

Chronic airway diseases treated by medication with breathing exercises

ACTIVE COMPARATOR

Chronic airway diseases treated by medication and breathing exercises

Behavioral: Breathing exercises

Interventions

Breathing exercises BEHAVIORAL

Breathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry

Also known as: Diaphragmatic Breathing exercise, Pursued lip breathing

Chronic airway diseases treated by medication with breathing exercises

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 \< 80% predicated together with an FEV1/FVC \<0.70confirm the presence of airflow limitation that is not fully reversible.
• COPD patients ranging from mild to severe according to GOLD \[stages I-IV\].
• Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).
• None of the individuals had been engaged in any exercise-training program before participating in the study.
• Optimized medical therapy according to GOLD \& Global Initiative for Asthma (GINA)
• Clinically stable COPD and asthmatic patients (not suffering from a recent respiratory tract infection).
• All patients are Ex-smoker

You may not qualify if:

• Age \<18 years.
• Pregnancy
• Current Smokers
• Patients that are incapable of exercising; unable to understand any questionnaire
• Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)
• Neuromuscular disease as Myasthenia gravis, kypho-scoliosis
• Diaphragmatic Paralysis (paralyzed diaphragm exhibiting abnormal paradoxical movement, i.e., moving in a cranial direction during inspiration).

Sponsors & Collaborators

• Mansoura University Hospital: lead

Study Sites (1)

Mohamed AbdElmoniem

Al Mansurah, 35516, Egypt

RECRUITING

MeSH Terms

Interventions

Breathing Exercises

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Mohamed AbdElmoniem

  Lecturer of chest medicine faculty of medicine Mansoura university

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed AbdElmoniem

CONTACT

01014008473; dr.m1993@mans.edu.eg

Mohamed Ahmed Ibrahim

CONTACT

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of chest medicine

Study Record Dates

• First Submitted: June 13, 2024
• First Posted: June 25, 2024
• Study Start: June 1, 2024
• Primary Completion: August 10, 2025
• Study Completion: December 10, 2025
• Last Updated: May 29, 2025

Record last verified: 2025-05

Locations

EG (1)