A Real World Study to Globally Assess Disease Burden in Adolescent and Adult Participants With Alopecia Areata, Vitiligo, or Hidradenitis Suppurativa

NCT07136467 | Recruiting

• 1 other identifier: H25-663
• Study Type: observational
• Target: 2,795
• Locations: 17 countries
• Sites: 114

Brief Summary

This study is to assess the burden of disease in adolescent and adult participants with moderate or severe alopecia areata (AA), non-segmental vitiligo (NSV), or moderate to severe hidradenitis suppurativa (HS) in a large global real-world participant population.

Conditions

Non-Segmental Vitiligo (NSV); Alopecia Areata; Hidradenitis Suppurativa

Keywords

Non-Segmental Vitiligo (NSV); Alopecia Areata; Hidradenitis Suppurativa

Outcome Measures

Primary Outcomes (6)

• Alopecia Areata (AA) symptoms affecting quality of life and daily functioning, assessed by the Alopecia Areata Symptom Impact Scale (AASIS) AA only

  AASIS- is a scale assessing the severity of AA-related symptoms on daily functioning. Each item scored on a 0-10 Likert scale, where 0 = not present and 10 = as bad as you can imagine Higher total score = greater impact

  Up to Day 1

• Measuring scalp hair loss, assessed by the Severity of Alopecia Tool (SALT) score. AA only

  SALT is a Tool developed to quantify AA-related hair loss Total score of 0-100, with 0 = no hair loss, and 100 = complete hair loss

  Up to Day 1

• Measuring facial skin depigmentation, assessed by the Facial Vitiligo Area Scoring Index (F-VASI) Vitiligo Only

  F-VASI is a quantitative scoring tool used to evaluate the extent and severity of facial vitiligo calculated by multiplying the degree of skin depigmentation of the face

  Up to Day 1

• Vitiligo Quality of Life (QOL), assessed by Vitiligo Quality of Life Score (VitiQoL) Vitiligo Only

  VitiQoL is a 16-item instrument assessing impact of vitiligo on QoL. 15 items are scored on a 7-point Likert scale, ranging from "not at all" to "all the time". An additional item (not contributing to total score) assesses current severity of condition on a 7-point scale ranging from "no skin involvement" to "most severe case"

  Up to Day 1

• Hidradenitis Suppurativa (HS) Quality of Life (QOL), assessed by Dermatology Life Quality Index (DLQI)/Children's Dermatology Life Quality Index (CDLQI) HS only

  CDLQI is a10-question index measuring health-related quality of life (HRQoL) over the last 7 days for patients suffering from a skin disease. The DLQI is used in participants aged 16 and over and the CDLQI has been validated from the ages of 4 to 16 years. Each item scored on a 4-point Likert scale, where 0 = not at all/not relevant/question unanswered and 3 = very much. Maximum total score = 30 (highest impact on QoL).

  Up to Day 1

• Measuring disease severity, assessed by the International Hidradenitis Suppurativa Severity Scoring System (IHS4) HS only

  The IHS4 score is calculated as follows: number of nodules (multiplied by 1) + number of abscesses (multiplied by 2) + number of draining tunnels (multiplied by 4). A total score of 3 or less signifies mild, 4 to 10 signifies moderate, and 11 or higher signifies severe disease.

  Up to Day 1

Study Arms (3)

Participants with Vitiligo

Participants with vitiligo will undergo a single-visit data collection per routine clinical practice

Participants with Alopecia Areata

Participants with alopecia areata will undergo a single-visit data collection per routine clinical practice

Participants with Hidradenitis Suppurativa

Participants with hidradenitis suppurativa will undergo a single-visit data collection per routine clinical practice

Eligibility Criteria

• Age: 12 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adolescent and Adult Participants with Alopecia Areata, Vitiligo, or Hidradenitis Suppurativa in Real-World will undergo a single-visit data collection per routine clinical practice.

You may qualify if:

• Participants with Physician-confirmed diagnosis of non-segmental vitiligo (NSV), moderate to severe Alopecia Areata (AA), or moderate to severe hidradenitis suppurativa (HS)
• Participants Ability to understand study questionnaires, with caregiver support as required for adolescents

You may not qualify if:

• Participating in interventional clinical trial(s) at time of study visit (participation in another non-interventional study or registry does not exclude a participant from this study)
• Unable or unwilling to comply with study requirements and PRO collection

Sponsors & Collaborators

• AbbVie: lead

Study Sites (116)

Hospital Britanico de Buenos Aires /ID# 278940

Ciudad Autonoma de Buenos Aire, Buenos Aires, 1280, Argentina

RECRUITING

Buenos Aires Skin /ID# 277637

Buenos Aires, 1055, Argentina

RECRUITING

Centro de Investigacion y Prevencion Cardiovascular (CIPREC) /ID# 277634

Buenos Aires, 1061, Argentina

RECRUITING

Hospital Italiano de Buenos Aires /ID# 277636

Buenos Aires, 1181, Argentina

RECRUITING

Instituto de Neumonología y Dermatología /ID# 277635

Buenos Aires, 1425, Argentina

RECRUITING

Dermatology Research Institute - Blackfoot Trail /ID# 276548

Calgary, Alberta, T2J 7E1, Canada

RECRUITING

Rejuvenation Dermatology - Edmonton Downtown /ID# 276593

Edmonton, Alberta, T5J 3S9, Canada

RECRUITING

Alberta Dermatology Consultants /ID# 277187

Edmonton, Alberta, T5N 1L5, Canada

RECRUITING

Brunswick Dermatology Center /ID# 276546

Fredericton, New Brunswick, R3M 3Z4, Canada

RECRUITING

Simcoderm Medical And Surgical Dermatology Centre /ID# 276838

Barrie, Ontario, L4M 7G1, Canada

RECRUITING

DermEffects /ID# 276594

London, Ontario, N6H 5L5, Canada

RECRUITING

Lynderm Research Inc /ID# 276595

Markham, Ontario, L3P 1X2, Canada

RECRUITING

York Dermatology Clinic & Research Centre /ID# 276697

Richmond Hill, Ontario, L4C 9M7, Canada

RECRUITING

Dermacentre Recherches /Id# 277593

Pointe-Claire, Quebec, H9R 5M7, Canada

RECRUITING

Centro de Inmunología y Genética CIGE SAS /ID# 280793

Medellín, Antioquia, 050012, Colombia

RECRUITING

Policlinico Social Del Norte /ID# 280935

Bogotá, Bogota D.C., 110131, Colombia

RECRUITING

Nemocnice Na Bulovce /ID# 275542

Prague, Central Bohemia, 180 81, Czechia

RECRUITING

Dermafit Centrum /ID# 275863

Pilsen, Plzeň Region, 323 00, Czechia

RECRUITING

Dermamedest /ID# 275861

Prague, Praha 2, 120 00, Czechia

RECRUITING

North Estonia Medical Centre /ID# 276933

Tallinn, Harju, 13419, Estonia

RECRUITING

Tartu University Hospital /ID# 276932

Tartu, 50406, Estonia

RECRUITING

Chu Dijon /Id# 277493

Dijon, Bourgogne-Franche-Comté, 21000, France

RECRUITING

Centre Hospitalier Regional Universitaire de Besancon - Hopital Jean Minjoz /ID# 277459

Besançon, Doubs, 25000, France

RECRUITING

Centre Hospitalier Universitaire de Bordeaux - Groupe Hospitalier Saint-Andre /ID# 277322

Bordeaux, Gironde, 33000, France

RECRUITING

CHU Toulouse - Hopital Larrey /ID# 277321

Toulouse, Haute-Garonne, 31400, France

RECRUITING

CHU Rennes - Hôpital PONTCHAILLOU /ID# 277527

Rennes, Ille-et-Vilaine, 35000, France

RECRUITING

Centre Hospitalier Régional Universitaire De Tours - Hôpital Trousseau /ID# 277545

Chambray-lès-Tours, Indre-et-Loire, 37170, France

RECRUITING

CHU Grenoble - Hopital Michallon /ID# 277501

La Tronche, Isere, 38700, France

RECRUITING

Centre Hospitalier de Bretagne Sud /ID# 277559

Lorient, Morbihan, 56322, France

RECRUITING

Centre Hospitalier Régional Metz Thionville - Hôpital de Mercy /ID# 277792

Metz, Moselle, 57085, France

RECRUITING

CHU Limoges - Dupuytren 2 /ID# 277323

Limoges, Nouvelle-Aquitaine, 87000, France

RECRUITING

Médipôle Lyon-Villeurbanne /ID# 277526

Villeurbanne, Rhone, 69100, France

RECRUITING

Groupe Hospitalier Du Havre - Hôpital Jacques Monod /ID# 277506

Montivilliers, Seine-Maritime, 76290, France

RECRUITING

Hopital Nord Franche-Comté /ID# 277560

Trévenans, Territoire De Belfort, 90400, France

RECRUITING

Hôpital d'Instruction des Armées Sainte-Anne /ID# 277458

Toulon, Var, 83800, France

RECRUITING

Centre Hospitalier Departemental Vendee (Chd Vendee) /ID# 277317

La Roche-sur-Yon, Vendee, 85925, France

RECRUITING

Centre Hospitalier de Calais /ID# 277320

Calais, 62100, France

RECRUITING

Centre Hospitalier Public du Cotentin - Hôpital Pasteur /ID# 279613

Cherbourg, 50102, France

RECRUITING

Cideazur /ID# 277316

Nice, 06000, France

RECRUITING

Centre De Santé Sabouraud /ID# 278409

Paris, 75010, France

RECRUITING

Groupe Hospitalier Paris Saint-Joseph /ID# 278270

Paris, 75014, France

RECRUITING

CHU de la reunion /ID# 277318

Saint-Denis, 97400, France

RECRUITING

Hôpital d'Instruction des Armées Bégin /ID# 278135

Saint-Mandé, 94163, France

RECRUITING

Mvz Corius Biberach Gmbh /Id# 281157

Biberach an der Riss, Baden-Wurttemberg, 88400, Germany

RECRUITING

Derma Sana /ID# 279254

Karlsruhe, Baden-Wurttemberg, 76133, Germany

RECRUITING

Private Practice - Dr. Virgil Oreste Mihaescu /ID# 279229

Augsburg, Bavaria, 86150, Germany

RECRUITING

Hautarztpraxis Hassberge Dr. Boris Bauer /ID# 279272

Haßfurt, Bavaria, 97437, Germany

RECRUITING

Dr. Neumann /ID# 279255

Kelheim, Bavaria, 93309, Germany

RECRUITING

Dermakulm /Id# 279126

Kulmbach, Bavaria, 95326, Germany

RECRUITING

Studienzentrum an der Hase GbR Dr. Weyergraf/Dr. Frick/Thomas Heiber /ID# 279210

Bramsche, Lower Saxony, 49565, Germany

RECRUITING

Hautarztliche Gemeinschaftspraxis Dres. med. Petri & Mocklinghoff /ID# 279230

Ahaus, North Rhine-Westphalia, 48683, Germany

RECRUITING

Hautarztpraxis Shirin Samimi-Fard & Elena Dippel /ID# 279232

Gladbeck, North Rhine-Westphalia, 45964, Germany

RECRUITING

ZENTderma /ID# 279235

Mönchengladbach, North Rhine-Westphalia, 41061, Germany

RECRUITING

Private Practice - Dr. Dariusch Mortazawi /ID# 279214

Remscheid, North Rhine-Westphalia, 42897, Germany

RECRUITING

Dermatologie Quist-BAG Dres. med. Quist PartG /ID# 279271

Mainz, Rhineland-Palatinate, 55128, Germany

RECRUITING

HMS GmbH Zimmer /ID# 279211

Merzig, Saarland, 66663, Germany

RECRUITING

Private Practice - Dr. Petra Hausler-Mehlhorn /ID# 280434

Chemnitz, Saxony, 09130, Germany

RECRUITING

Private Practice - Dr. Abdou Zarzour /ID# 279125

Halle, Saxony-Anhalt, 06108, Germany

RECRUITING

Private Practice - Dr. Dirk Lange /ID# 279215

Gera, Thuringia, 07548, Germany

RECRUITING

MVZ medicum.mittelhessen /ID# 279136

Bad Camberg, 65520, Germany

RECRUITING

Hautarztpraxis Dr. Med. Ulrike Wiemers / Dr. Med. Franca Wiemers /ID# 279124

Leipzig, 04317, Germany

RECRUITING

Hautarztpraxis Schwelm /ID# 279140

Schwelm, 58332, Germany

RECRUITING

Praxis Dehmel / Brand-Opitzer /ID# 279351

Wasserburg A. Inn, 83512, Germany

RECRUITING

Dr. med. Nicola Möller & Thomas Kurtenbach GbR Dermatologie im Zentrum /ID# 279137

Wiesbaden, 65185, Germany

RECRUITING

University General Hospital Attikon /ID# 278395

Athens, Attica, 12462, Greece

RECRUITING

General Hospital Andreas Syggros /ID# 276969

Athens, Attica, 16121, Greece

RECRUITING

Tzaneio Prefecture General Hospital of Piraeus /ID# 276881

Piraeus, Attica, 18536, Greece

RECRUITING

The University Hospital of Larissa /ID# 277234

Larissa, Larisa, 41110, Greece

RECRUITING

Hospital of Skin and Venereal Diseases- Thessaloniki /ID# 277278

Thessaloniki, 54643, Greece

RECRUITING

Papageorgiou General Hospital /ID# 277450

Thessaloniki, 56429, Greece

RECRUITING

Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale S.Anna /ID# 276986

Cona, Ferrara, 44124, Italy

RECRUITING

Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 277745

Rome, Roma, 00168, Italy

RECRUITING

A.O.U. Consorziale Policlinico di Bari /ID# 276857

Bari, 70124, Italy

RECRUITING

Nagomi Dermatology Clinic /ID# 279997

Ebina-shi, Kanagawa, 243-0432, Japan

RECRUITING

Shinsaibashi Inui Dermatology Clinic /ID# 280564

Osaka, Osaka, 542-0081, Japan

RECRUITING

Inokashira Park Skin Clinic /ID# 279276

Mitaka-shi, Tokyo, 1810013, Japan

RECRUITING

Omori Ekimae Dermatology Clinic /ID# 279277

Ōta-ku, Tokyo, 143-0016, Japan

RECRUITING

Riga 1st Hospital /ID# 276361

Riga, LV-1001, Latvia

RECRUITING

Dermatologia Borinquen LLC /ID# 276802

Caguas, 00725, Puerto Rico

RECRUITING

Dr. Samuel Sanchez PSC /ID# 276386

Caguas, 00727, Puerto Rico

RECRUITING

Clinical Research Puerto Rico /ID# 276801

San Juan, 00909, Puerto Rico

RECRUITING

Institutul Dermato - Estetic /ID# 276296

Bucharest, București, 010235, Romania

RECRUITING

Dr. Carol Davila Central Military Emergency University Hospital /ID# 275818

Bucharest, București, 010825, Romania

RECRUITING

Spitalul Universitar De Urgență Elias /ID# 275806

Bucharest, București, 011461, Romania

RECRUITING

Spitalul Clinic Colentina /ID# 275506

Bucharest, București, 020125, Romania

RECRUITING

Spitalul Clinic Colentina /ID# 275817

Bucharest, București, 020125, Romania

RECRUITING

Spitalul Clinic Judetean de Urgenta Cluj -Napoca /ID# 276837

Cluj-Napoca, Cluj, 400006, Romania

RECRUITING

Spitalul Clinic Județean de Urgențe "Sfântul Spiridon" /ID# 276308

Iași, 700111, Romania

RECRUITING

Yonsei University Health System Severance Hospital /ID# 278972

Seoul, Seoul Teugbyeolsi, 03722, South Korea

RECRUITING

Yonsei University Health System Severance Hospital /ID# 278973

Seoul, Seoul Teugbyeolsi, 03722, South Korea

RECRUITING

Hospital Universitario de Jaén /ID# 276888

Jaén, Jaen, 23007, Spain

RECRUITING

Hospital Universitario Fundación Alcorcón /ID# 276890

Alcorcón, Madrid, 28922, Spain

RECRUITING

Hospital Universitario Puerta de Hierro - Majadahonda /ID# 276731

Majadahonda, Madrid, 28222, Spain

RECRUITING

Hospital Universitario Infanta Cristina /ID# 276886

Parla, Madrid, 28981, Spain

RECRUITING

Hospital Universitario de Canarias /ID# 276734

San Cristóbal de La Laguna, Santa Cruz De Tenerife, 38320, Spain

RECRUITING

Hospital Arnau De Vilanova /ID# 276887

Valencia, 46015, Spain

RECRUITING

Kantonsspital Aarau /ID# 276810

Aarau, Canton of Aargau, 5001, Switzerland

RECRUITING

University Hospital Basel /ID# 276716

Basel Town, Canton of Basel-City, 4031, Switzerland

RECRUITING

Cabinet Dr Damjan Nikolic, Clinique du Seujet /ID# 278467

Geneva, Canton of Geneva, 1201, Switzerland

RECRUITING

Hopitaux Universitaires de Geneve /ID# 277950

Geneva, Canton of Geneva, 1205, Switzerland

RECRUITING

Luzern Kantonsspital /ID# 276813

Lucerne, Canton of Lucerne, 6000, Switzerland

RECRUITING

Praxis Dr. med. Pierre de Viragh /ID# 276855

Zurich, Canton of Zurich, 8002, Switzerland

RECRUITING

Ospedale Regionale Bellinzona E Valli /ID# 277964

Bellinzona, Canton Ticino, 6501, Switzerland

RECRUITING

Studio Medico Dr. Pelloni Francesco /ID# 277948

Lugano, Canton Ticino, 6900, Switzerland

RECRUITING

Basile Darbellay SA /ID# 276811

Orsières, Valais, 1937, Switzerland

RECRUITING

Inselspital, Universitaetsspital Bern /ID# 276718

Bern, 3010, Switzerland

RECRUITING

Tri-Service General Hospital /ID# 279761

Taipei, 114, Taiwan

RECRUITING

Linkou Chang Gung Memorial Hospital /ID# 279760

Taoyuan, 333, Taiwan

RECRUITING

University Hospital Lewisham /ID# 279233

London, Greater London, SE13 6LH, United Kingdom

RECRUITING

Oxford University Hospitals - John Radcliffe Hospital /ID# 279052

Oxford, Oxfordshire, OX3 9DU, United Kingdom

RECRUITING

Leeds Teaching Hospitals NHS Trust /ID# 278524

Leeds, West Yorkshire, LS9 7TF, United Kingdom

RECRUITING

Mid Yorkshire Teaching NHS Trust /ID# 279190

Wakefield, West Yorkshire, WF1 4DG, United Kingdom

RECRUITING

Ulster Hospital - South Eastern Health & Social Care Trust /ID# 279191

Belfast, BT16 1RH, United Kingdom

RECRUITING

Cardiff and Vale UHB /ID# 278856

Cardiff, CF14 4XW, United Kingdom

RECRUITING

Walsall Manor Hospital /ID# 279240

Walsall, WS2 9PS, United Kingdom

RECRUITING

New Cross Hospital /ID# 279202

Wolverhampton, WV10 0QP, United Kingdom

RECRUITING

Related Links

• Related Info

MeSH Terms

Conditions

Alopecia Areata; Hidradenitis Suppurativa

Condition Hierarchy (Ancestors)

Alopecia; Hypotrichosis; Hair Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Skin Diseases, Bacterial; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Skin Diseases, Infectious; Suppuration; Hidradenitis; Sweat Gland Diseases

Study Officials

• ABBVIE INC.

  AbbVie

  STUDY DIRECTOR

Central Study Contacts

Beth Rycroft

CONTACT

844-663-3742; beth.rycroft@abbvie.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 31, 2025
• First Posted: August 22, 2025
• Study Start: September 2, 2025
• Primary Completion (Estimated): August 1, 2027
• Study Completion (Estimated): August 1, 2027
• Last Updated: February 13, 2026

Record last verified: 2026-02

Locations

CZ (3); KR (2); GR (6); IT (3); FR (22); GB (8); CA (9); LA (1); AR (5); JP (4); PR (3); DE (21); RO (7); TW (2); ES (6); CO (2); CH (10)