Key Insights

Highlights

Success Rate

84% trial completion

Published Results

44 trials with published results (24%)

Research Maturity

81 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 39/100

Termination Rate

8.1%

15 terminated out of 185 trials

Success Rate

84.4%

-2.1% vs benchmark

Late-Stage Pipeline

22%

40 trials in Phase 3/4

Results Transparency

54%

44 of 81 completed with results

Key Signals

44 with results84% success15 terminated

Data Visualizations

Phase Distribution

154Total
Not Applicable (36)
Early P 1 (6)
P 1 (14)
P 2 (58)
P 3 (18)
P 4 (22)

Trial Status

Completed81
Unknown37
Recruiting29
Terminated15
Active Not Recruiting9
Withdrawn7

Trial Success Rate

84.4%

Benchmark: 86.5%

Based on 81 completed trials

Clinical Trials (185)

Showing 20 of 20 trials
NCT05391178Not ApplicableCompleted

Improving Disease Severity

NCT07226531RecruitingPrimary

Utilization and Effectiveness of Ritlecitinib in a Real-World Population With Severe AA in the US

NCT07533006Phase 2RecruitingPrimary

A Study of LY4005130 in Adult Participants With Severe Alopecia Areata (Hair Loss)

NCT06012240Phase 3RecruitingPrimary

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

NCT03570749Phase 2CompletedPrimary

A Study of Baricitinib (LY3009104) in Participants With Severe or Very Severe Alopecia Areata

NCT06104839Phase 2RecruitingPrimary

Safety and Efficacy of Oral NXC-736 in Adult Participants With Moderate and Severe Alopecia Areata

NCT04006457Phase 3CompletedPrimary

Long-Term PF-06651600 for the Treatment of Alopecia Areata

NCT06340360Phase 2Active Not RecruitingPrimary

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Severe to Very Severe Alopecia Areata in Adult Patients (Rezolve AA)

NCT07499713Enrolling By InvitationPrimary

Association of Serum VEGF-A and VCAM-1 Levels With Nailfold Capilleroscopic Alterations in Alopecia Areata

NCT02557074Phase 3CompletedPrimary

TREg Activation in the Treatment of the PELADE (Alopecia Areata)

NCT03661866Active Not Recruiting

A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC

NCT07459933Phase 4Not Yet RecruitingPrimary

Topical Methotrexate vs Minoxidil for Localized Alopecia Areata

NCT07454876CompletedPrimary

Association of TLR7 Gene rs3853839 Polymorphism With Disease Severity in Alopecia Areata: A Case-Control Study

NCT07453238Phase 4Not Yet RecruitingPrimary

Comparison of Topical Calcipotriol and Intralesional Steroids in Alopecia Areata

NCT06279221Active Not RecruitingPrimary

Litfulo Capsules Special Investigation

NCT06531109RecruitingPrimary

Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib

NCT05866562Phase 2RecruitingPrimary

Dupilumab in the Treatment of Pediatric Alopecia Areata

NCT07136467Recruiting

A Real World Study to Globally Assess Disease Burden in Adolescent and Adult Participants With Alopecia Areata, Vitiligo, or Hidradenitis Suppurativa

NCT07406204Phase 4Not Yet RecruitingPrimary

Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA)

NCT05745389RecruitingPrimary

CorEvitas Alopecia Areata (AA) Safety and Effectiveness Registry

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