Functional Exercise Performance in Children With Cerebral Palsy: Is the One-Minute Sit-to-Stand Test an Alternative to the Six-Minute Walk Test

NCT07136129 | Completed

• 1 other identifier: SP-1sts6dyt
• Study Type: observational
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the validity of the 1-minute sit-to-stand test (1MSTS) as a practical and time-efficient alternative to the 6-minute walk test (6MWT) for assessing functional exercise capacity in children with spastic cerebral palsy (CP). Children aged 5 to 18 years with spastic hemiplegic CP, classified as Level I or II according to the Gross Motor Function Classification System (GMFCS), will perform both tests on the same day. Cardiopulmonary responses and fatigue will be monitored before and after each test. The study aims to determine whether the 1MSTS can be reliably used in clinical settings as a simpler assessment tool for this population.

Conditions

Cerebral Palsy; Cerebral Palsy Spastic Hemiplegic

Keywords

cerebral palsy; One-Minute Sit-to-Stand Test; Functional Exercise Performance in Cerebral Palsy; Six-Minute Walk Test

Outcome Measures

Primary Outcomes (2)

• Number of Repetitions in the 1-Minute Sit-to-Stand Test (1MSTS)

  This outcome measures the total number of full sit-to-stand movements performed in one minute by participants with spastic hemiplegic cerebral palsy. The aim is to determine whether the 1MSTS is a valid measure of functional exercise performance in this population.

  At baseline (single assessment session)

• Distance Walked in the 6-Minute Walk Test (6MWT)

  Measures the total distance (in meters) walked in 6 minutes by participants on a 30-meter corridor, in accordance with ATS guidelines. The 6MWT serves as the reference test to compare with the 1MSTS.

  At baseline (single assessment session)

Secondary Outcomes (4)

• Heart Rate (HR) Before and After Exercise Tests

  Pre-intervention and immediately after the intervention

• Oxygen Saturation (SpO2) Before and After Exercise Tests

  Pre-intervention and immediately after the intervention

• Systolic and Diastolic Blood Pressure Before and After Exercise Tests

  Pre-intervention and immediately after the intervention

• Perceived Dyspnea and Leg Fatigue Using Modified Borg Scale

  Pre-intervention and immediately after the intervention

Study Arms (1)

Spastic hemiplegic type SP

Individuals between 5 and 18 years of age, diagnosed with spastic hemiplegic type CP and in level I or II according to the Gross Motor Function Classification System (GMFCS) were included.

Eligibility Criteria

• Age: 5 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of children aged between 5 and 18 years who were diagnosed with spastic hemiplegic type cerebral palsy (CP) and were being followed up at the Physical Therapy and Rehabilitation Clinic of Kayseri City Hospital between December 2024 and July 2025. These individuals were classified as Level I or II according to the Gross Motor Function Classification System (GMFCS), indicating relatively high levels of functional mobility. All participants and their legal guardians were informed about the study's purpose and procedures, and written informed consent was obtained. The study was approved and conducted in accordance with the principles of the Declaration of Helsinki.

You may qualify if:

• Having spastic hemiplegic CP between 5-18
• Being level 1 and 2 according to KMFSS

You may not qualify if:

• Having cognitive/mental problems at a level that may prevent communication
• Having genetic and/or neurological problems in addition to CP
• Having uncontrolled heart disease
• Having any infection Removal Criteria
• The child or his/her parents wanting to leave the study
• Failure to complete the tests to be applied within the scope of the study
• Having an additional disease/surgical operation during the study

Sponsors & Collaborators

• Inonu University: lead
• Kayseri University: collaborator

Study Sites (1)

Kayseri City Hospital

Kayseri, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: research asistant

Study Record Dates

• First Submitted: July 10, 2025
• First Posted: August 22, 2025
• Study Start: December 31, 2024
• Primary Completion: March 1, 2025
• Study Completion: July 1, 2025
• Last Updated: August 22, 2025

Record last verified: 2025-07

Locations

TU (1)