The Relationship Between Early Motor Repertoire Quality and Later-term Motor Function in Children With CP

NCT07498101 | Completed DMC

• 1 other identifier: Uskudaraysesav
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Cerebral palsy (CP) is a group of disorders attributed to non-progressive disorders occurring in the developing fetal, infantile brain, affecting posture, movement development, and activity limitations. It occurs in approximately 2 to 2.5 per 1,000 live births. The prognosis for gross motor function among children with CP is extremely variable. This variability poses a significant challenge to scientific definitions of motor function for clinicians who regularly deal with practical issues such as examination, prognosis, intervention planning, and outcome assessment in children with CP. Observing the general quality of movement of preterm or term babies can be used to identify babies at risk of developing neurological disorders and can provide information about possible future motor function.

Conditions

Cerebral Palsy

Keywords

cerebral palsy; Gross Motor Function; EARLY MOTOR REPERTOIRE QUALITY; LATER-TERM MOTOR FUNCTION

Outcome Measures

Primary Outcomes (2)

• Motor Optimality Score (MOS)

  Motor optimality score (MOS) have 5 categories to the score. These are fidgety movements (max 12 points), repertoire of co-existent other movements (max 4 points), quality of other movements (max 4 points), posture (max 4 points) and movement character (max 4 points). The category scores are added to a max of 28 points.

  3 months

• Gross Motor Function Measurement (GMFM-66)

  The Gross Motor Function Measure (GMFM) is a tool that has been developed to assess change in gross motor function in children with cerebral palsy aged 5 months to 16 years of age.1 The GMFM measures 'activity' as defined within the Interna- tional Classification of Functioning, Disability and Health.2 To administer the GMFM, a trained therapist observes the child completing a number of gross motor tasks in a standardised environment, and the child's best ability is measured.

  3 months

Study Arms (1)

1

Babies aged between 3 months and 5 months (corrected age) who applied to the Turkish Spastic Children Foundation for risky baby evaluation between 2011 and 2023, whose videos were recorded for GM's evaluation, and who were later diagnosed with cerebral palsy will be included in the study. The quality of the early engine repertoire will be evaluated with MOS (Motor Optimality Score) based on GM's video footage. The evaluation will be carried out by a physiotherapist who has received advanced GM's evaluation training.

Eligibility Criteria

• Age: 3 Months - 5 Months
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

Children diagnosed with Cerebral Palsy who applied to the Turkish Spastic Children Foundation for evaluation between 2011 and 2023 and whose Prechtl Analysis shots were archived between the 10th and 20th weeks will be included in the study.

You may qualify if:

• Children with a diagnosis of Cerebral Palsy
• Children who applied to the Turkish Spastic Children Foundation between 2011-2023
• Availability of Prechtl General Movements Assessment recordings obtained between 10-20 weeks post-term age
• Availability of GMFM-66 assessment data

You may not qualify if:

• Lack of parental or legal guardian consent
• Presence of additional diagnoses affecting motor assessment
• Cases where GMFM-66 evaluation was not applicable
• Incomplete clinical records

Sponsors & Collaborators

• Uskudar University: lead

Study Sites (1)

Türkiye Spastik Çocuklar Vakfı

Istanbul, Ataşehir, 34750, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, Chronic; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• osman çoban, phD

  Uskudar University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asst. Prof.

Study Record Dates

• First Submitted: March 23, 2026
• First Posted: March 27, 2026
• Study Start: December 1, 2023
• Primary Completion: January 30, 2024
• Study Completion: January 30, 2024
• Last Updated: March 30, 2026

Record last verified: 2026-03

Locations

TU (1)