COVID-19 Infection and Thoracic Anesthesia?

NCT07118917 | Completed

• 1 other identifier: 2024/667
• Study Type: observational
• Target: 110
• Locations: 1 country
• Sites: 1

Brief Summary

SARS-CoV-2 has infected more than 776 million people worldwide, raising concerns about its impact on patients with lung cancer, the most common cancer in men and the second most common cancer in women. Previous studies have suggested that COVID-19 may worsen lung dysfunction in patients undergoing surgery and that the coexistence of COVID-19 and lung cancer increases the risk of complications and mortality. It has been recommended that surgery be delayed after COVID-19 infection to reduce postoperative risk. This study examined the effects of prior COVID-19 infection on respiratory mechanics in patients undergoing thoracic surgery for lung cancer.

Conditions

COVID - 19; Thoracic Anesthesia; Mechanical Power

Outcome Measures

Primary Outcomes (1)

• Mechanical Power Calculation

  Intraoperative period ( Day of Surgery)

Secondary Outcomes (1)

• Plato Pressure

  Intraoperative period ( Day of Surgery)

Study Arms (2)

COVID-19 positive

COVID-19 positive patients

Other: Prehabilitation

COVID-19 negative

COVID-19 negative

Other: No postponement

Interventions

Prehabilitation OTHER

Patients with COVID-19 history postponed for the surgery according to multidisciplinary decision.

COVID-19 positive

No postponement OTHER

Patients who were COVID negative proceeded for surgery

COVID-19 negative

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients operated for thoracic surgery

You may qualify if:

• age ≥18 years and planned procedures, including pneumonectomy, lobectomy, segmentectomy, or other lung resections

You may not qualify if:

• patient refusal to participate and inability to provide informed consent due to psychological or mental incapacity.

Sponsors & Collaborators

• Ankara University: lead

Study Sites (1)

Ankara University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

COVID-19

Interventions

Preoperative Exercise

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Perioperative Care; Patient Care; Therapeutics; Surgical Procedures, Operative; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Health Services; Health Care Facilities Workforce and Services

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: June 24, 2025
• First Posted: August 12, 2025
• Study Start: September 12, 2024
• Primary Completion: June 5, 2025
• Study Completion: June 5, 2025
• Last Updated: August 12, 2025

Record last verified: 2025-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)