Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure
1 other identifier
interventional
80
1 country
1
Brief Summary
This a prospective study to compare between clipping and ligation of appendicular stump in laparoscopic appendectomies regarding ;technical feasibility , post operative complications as fecal fistula and economic consideration.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jul 2025
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 14, 2025
CompletedFirst Submitted
Initial submission to the registry
August 4, 2025
CompletedFirst Posted
Study publicly available on registry
August 11, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 28, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
February 28, 2026
CompletedAugust 11, 2025
August 1, 2025
8 months
August 4, 2025
August 4, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Results of Laparoscopic Appendectomy with application of clips versus ligature for stump closure
postoperative hospital stay
24 hours postoperative
Study Arms (2)
Laparoscopic Appendectomy with application of clips for stump closure
ACTIVE COMPARATORLaparoscopic Appendectomy with ligature for stump closure
ACTIVE COMPARATORInterventions
in patients who will undergo Laparoscopic Appendectomy, appendicular stump will be closed by application of clips
in patients who will undergo Laparoscopic Appendectomy, appendicular stump will be closed by ligation
Eligibility Criteria
You may qualify if:
- Any patient diagnosed with acute appendicitis of any age and of any sex presented to ER of the Department of General, Laparoscopic and Oncologic Surgery Department, Sohag University Hospital will be enrolled in this study.
You may not qualify if:
- Patients with complicated appendicitis.
- Patients with unstable cardiac or pulmonary condition.
- Patients with suspicious crhon's disease or mass intraoperative.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Sohag Universitylead
Study Sites (1)
Sohag university hospital
Sohag, Egypt
Related Publications (3)
Makaram N, Knight SR, Ibrahim A, Patil P, Wilson MSJ. Closure of the appendiceal stump in laparoscopic appendectomy: A systematic review of the literature. Ann Med Surg (Lond). 2020 Aug 4;57:228-235. doi: 10.1016/j.amsu.2020.07.058. eCollection 2020 Sep.
PMID: 32802324BACKGROUNDFarahani PK, Safaei N. Comparison of two methods: Clipping and suturing in laparoscopic appendectomy. Surg Open Sci. 2024 May 3;19:162-165. doi: 10.1016/j.sopen.2024.04.007. eCollection 2024 Jun.
PMID: 38764557BACKGROUNDPoon SHT, Law SY, Lai ATY. Clips closure versus endoloop ligation in laparoscopic appendectomy: a systematic review and meta-analysis of comparative studies. Ann Med Surg (Lond). 2023 Sep 6;85(10):5011-5021. doi: 10.1097/MS9.0000000000001260. eCollection 2023 Oct.
PMID: 37811063BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident of General, Oncologic& Laparscopic Surgery Faculty of Medicine, Sohag University
Study Record Dates
First Submitted
August 4, 2025
First Posted
August 11, 2025
Study Start
July 14, 2025
Primary Completion
February 28, 2026
Study Completion
February 28, 2026
Last Updated
August 11, 2025
Record last verified: 2025-08