Acute Effects of Aerobic Exercise and High-intensity Interval Exercise With Immersive Virtual Reality

NCT07101341 | Not Yet Recruiting

• 1 other identifier: 2024-FIS-3483189
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to compare the acute effects at the cardiovascular (heart rate, blood pressure) and physiological (lactate) levels, as well as the perception of effort and fatigue, of four exercise modalities, one based on the traditional aerobic training methodology, another based on high-intensity interval training (HIIT), another consisting of aerobic exercise performed in conjunction with an immersive virtual reality (VR) application, and a last one consisting of exercise with HIIT-type parameters but also performed in conjunction with an immersive VR application. All participants will complete one session of each of the four exercise modalities, analyzing the variables studied in each for subsequent analysis and comparison.

Conditions

Acute Effects of Exercise in Healthy People; Health Adult Subjects

Keywords

virtual reality; immersive virtual reality; exergame

Outcome Measures

Primary Outcomes (1)

• Blood lactate

  Analysis of blood lactate concentration

  During the 5 minutes after finishing the exercise session of each intervention modality (Days 1, 8, 15 and 22 from the start of the study)

Secondary Outcomes (5)

• Heart rate pattern

  During each exercise session (Days 1, 8, 15 and 22 from the start of the study)

• Systolic and diastolic blood pressure

  During the 5 minutes after finishing the exercise session of each intervention modality (Days 1, 8, 15 and 22 from the start of the study)

• Perception of effort

  During the first minute after finishing the exercise session of each intervention modality (Days 1, 8, 15 and 22 from the start of the study)

• Perception of fatigue

  During the first minute after finishing the exercise session of each intervention modality (Days 1, 8, 15 and 22 from the start of the study)

• Physical performance

  During the 5 minutes after finishing the exercise session of each intervention modality (Days 1, 8, 15 and 22 from the start of the study)

Study Arms (4)

Traditional aerobic exercise

EXPERIMENTAL

Procedure: Traditional aerobic training

High-intensity interval training

EXPERIMENTAL

A single session of exercise

Procedure: High Intensity Interval Training (HIIT)

Aerobic exercise applied with reality virtual

EXPERIMENTAL

A single session of exercise

Procedure: Aerobic training performed with a immersive virtual reality application

High-intensity interval training applied with virtual reality

EXPERIMENTAL

A single session of exercise

Procedure: High Intensity Interval Training (HIIT) performed with a immersive virtual reality application

Interventions

Traditional aerobic training PROCEDURE

5 minutes of warm-up at increasing intensity up to 60% of maximum heart rate (HRmax) + 20 minutes between 60-80% of HRmax + 5 minutes of cool-down at decreasing intensity (30-60% HRmax)

Traditional aerobic exercise

High Intensity Interval Training (HIIT) PROCEDURE

5 minutes warm-up at increasing intensity up to 60% maximum heart rate (HRmax) + 20 minutes main part consisting of 10 repetitions of the combination of 1 minute at 75-90% HRmax and 2 minutes of active rest with light pedaling (50% HRmax) + 5 minutes cool-down at decreasing intensity (30-60% HRmax)

High-intensity interval training

Aerobic training performed with a immersive virtual reality application PROCEDURE

5 minutes of warm-up at increasing intensity up to 60% Maximum heart rate (HRmax) + 20 minutes between 60-80% of HRmax + 5 minutes of cooling at decreasing intensity (30-60% HRmax), with the use of virtual reality glasses and an immersive virtual reality application

Aerobic exercise applied with reality virtual

High Intensity Interval Training (HIIT) performed with a immersive virtual reality application PROCEDURE

5 minutes warm-up at increasing intensity up to 60% Maximum heart rate (HRmax) + 20 minutes main part consisting of 10 repetitions of the combination of 1 minute at 75-90% HRmax and 2 minutes of active rest with light pedaling (50% HRmax) + 5 minutes cool-down at decreasing intensity (30-60% HRmax), with the use of virtual reality glasses for an immersive virtual reality application

High-intensity interval training applied with virtual reality

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy people between 18 and 35 years old

You may not qualify if:

• Current or recent injury that affects training
• Condition that prevents exercise (decompensated heart disease, decompensated respiratory disease, significant mobility difficulties, etc.)
• Visual problems that prevent exercise with virtual reality headsets

Sponsors & Collaborators

• University of Valencia: lead

Study Sites (1)

Faculty of Physiotherapy, University of Valencia

Valencia, Valencia, 46010, Spain

Location

MeSH Terms

Interventions

High-Intensity Interval Training

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Adrian Escriche-Escuder, PhD

  University of Valencia

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Adrian Escriche-Escuder, PhD

CONTACT

+34 963 98 38 55; adrian.escriche@uv.es

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: July 22, 2025
• First Posted: August 3, 2025
• Study Start: January 1, 2026
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: November 19, 2025

Record last verified: 2025-11

Locations

ES (1)