Relationship Between Serum Markers and Motor Recovery and Ambulation in Post-stroke Patients

NCT07086092 | Completed

• 1 other identifier: AIBU-FTR-SK-11
• Study Type: observational
• Target: 257
• Locations: 1 country
• Sites: 1

Brief Summary

This study aim to retrospectively investigate the effects of the magnesium, vitamin D, and uric acid serum markers on motor recovery and ambulation in post-stroke patients.

Conditions

Stroke; Biomarkers; Serum Magnesium; Serum Vitamin D; Serum Uric Acid

Outcome Measures

Primary Outcomes (5)

• Serum magnesium levels

  Serum magnesium levels measured before the patients' rehabilitation will be obtained from past medical records.

  Before treatment

• Serum uric acid levels

  Serum uric acid levels measured before the patients' rehabilitation will be obtained from past medical records.

  Before treatment

• Serum vitamin D levels

  Serum vitamin D levels measured before the patients' rehabilitation will be obtained from past medical records.

  Before treatment

• Brunnstrom Motor Recovery Stage

  Brunnstrom stages is a scale used to assess motor recovery after a stroke, which is expressed using values between 1 and 6. The higher the value on this scale, the higher would be the recovery. Brunnstrom Motor Recovery Stages measured before the patients' rehabilitation will be obtained from past medical records.

  Before treatment

• Functional Ambulation Classification

  Functional Ambulation Classification is a 6-point functional walking test that evaluates ambulation ability and determines the amount of human support required by patients while walking, regardless of whether they use a personal assistive device. A score of 0 indicates that the patient has a dysfunctional ambulation A score of 5 denotes independent ambulation on any surface. Functional Ambulation Classification Stages measured before the patients' rehabilitation will be obtained from past medical records.

  Before treatment

Interventions

Serum magnesium, uric acid, and vitamin D levels and motor recovery and ambulation stages OTHER

Serum magnesium, uric acid, and vitamin D levels, as well as motor recovery and ambulation levels, measured during the patients' rehabilitation stay will be obtained from past medical records.

Eligibility Criteria

• Age: 30 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who have had a stroke for the first time and are hospitalized in the rehabilitation ward for rehabilitation purposes.

You may qualify if:

• Patients who had a single stroke between 2019 and 2024
• Patients who were admitted to the rehabilitation ward and had their serum vitamin D, magnesium, and uric acid levels measured
• Patients whose functional ambulation scale scores and Brunnstrom motor recovery stages were recorded

You may not qualify if:

• Patients with other neurological diseases
• Patients with multiple strokes
• Patients with gout, renal failure, or hyperparathyroidism

Sponsors & Collaborators

• Abant Izzet Baysal University: lead

Study Sites (1)

Abant Izzet Baysal University

Bolu, 14100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Stroke

Interventions

Uric Acid

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: July 18, 2025
• First Posted: July 25, 2025
• Study Start: July 15, 2025
• Primary Completion: July 15, 2025
• Study Completion: July 15, 2025
• Last Updated: July 29, 2025

Record last verified: 2025-07

Locations

TU (1)