Impact of Processing Speed on Motor, Balance, Gait, and Quality of Life in Stroke"

NCT07159256 | Enrolling By Invitation

• 1 other identifier: IstanbulIAU
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke rehabilitation programs are traditionally designed based on the evaluation of motor and sensory impairments starting from the acute phase. Although studies in diseases such as multiple sclerosis and Parkinson's disease have shown that information processing speed may affect motor function and balance, no such study has been conducted in stroke patients. This study aims to investigate the effect of information processing speed on motor function, balance, gait, and quality of life in patients with ischemic stroke.

Conditions

Stroke; Ischaemic Stroke

Keywords

Information Processing Speed; Motor Function; Balance; Gait; Quality of Life; ischaemic stroke

Outcome Measures

Primary Outcomes (1)

• Symbol Digit Modalities Test (SDMT) Score

  The Symbol Digit Modalities Test (SDMT) will be used to assess information processing speed. The test requires participants to match symbols with corresponding numbers according to a reference key within 90 seconds. The total number of correct responses will be recorded, with higher scores indicating better processing speed.

  At baseline (single assessment)

Secondary Outcomes (5)

• Berg Balance Scale (BBS) Score

  At baseline (single assessment)

• Fugl-Meyer Assessment (FMA) Score

  At baseline (single assessment)

• Stroke-Specific Quality of Life Scale (SS-QOL) Score

  At baseline (single assessment)

• Balance Assessment with Sense4Motion Euleria Health / Euleria Lab Device

  At baseline (single assessment)

• Timed Up and Go Test (TUG) with Euleria Health / Euleria Lab

  At baseline (single assessment)

Study Arms (1)

Single Group Assignment

All participants will be patients diagnosed with first-ever ischemic stroke, aged 40 years or older, hemodynamically stable, literate, and without pre-stroke psychiatric, neurological, visual, auditory, or orthopedic conditions that could affect mobilization. Participants will undergo a series of standardized assessments including information processing speed (Symbol Digit Modalities Test), motor function (Fugl-Meyer Assessment), balance (Berg Balance Scale and Sense4Motion Euleria Health device), gait (Timed Up and Go Test), and quality of life (Stroke-Specific Quality of Life Scale). The aim is to evaluate the relationship between processing speed and functional outcomes in ischemic stroke rehabilitation.

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of adult patients aged 40-74 years who experienced a first-ever ischemic stroke and are hemodynamically stable. Eligible participants will be literate, without prior psychiatric, neurological, visual, auditory, or orthopedic conditions affecting mobilization. Patients must have full scores in the vision and speech domains of the NIH Stroke Scale (NIHSS) after stroke. Individuals with recurrent stroke, severe cognitive or language impairments, post-stroke visual or auditory deficits, neglect, cardiovascular or orthopedic conditions preventing mobilization, or those aged 75 years and older will be excluded.

You may qualify if:

• Age 40 years or older
• First-ever ischemic stroke
• Hemodynamically stable
• Able to read and write (literate)
• No history of psychiatric, neurological, visual, auditory, or orthopedic conditions prior to stroke that could affect mobilization
• After stroke, full scores in the vision and speech domains according to the NIH Stroke Scale (NIHSS)

You may not qualify if:

• Recurrent stroke
• Post-stroke visual or hearing impairment
• Neglect
• Aphasia
• Conditions causing impaired consciousness such as dementia, confusion, or delirium
• Presence of cardiovascular or orthopedic conditions after stroke that prevent mobilization
• Age 75 years or older

Sponsors & Collaborators

• Istanbul Aydın University: lead

Study Sites (1)

Istanbul Aydın University

Istanbul, Küçükçekmece, 34295, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Stroke; Ischemic Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Gökhan ÖZKOÇAK, MD

  Istanbul Aydın University

  STUDY CHAIR

• Özden Erkan Oğul, Asst. Prof

  Medipol University

  STUDY CHAIR

• İbrahim H Ural, MD

  Beykent University

  STUDY CHAIR

• Arzu DİNÇ YAVAŞ, MD

  Istanbul Aydın University

  STUDY CHAIR

• Dudu K AKYOL, PT

  Istanbul Aydın University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 29, 2025
• First Posted: September 8, 2025
• Study Start: September 5, 2025
• Primary Completion: October 7, 2025
• Study Completion: November 7, 2025
• Last Updated: September 11, 2025

Record last verified: 2025-09

Locations

TU (1)