EFFECTS OF IRRIGATION NEEDLES WITH DIFFERENT DESIGNS USED DURING ENDODONTIC TREATMENT ON POSTOPERATIVE PAIN

NCT07080918 | Completed

• 1 other identifier: 143
• Study Type: interventional
• Target: 66
• Locations: 1 country
• Sites: 1

Brief Summary

This study is aimed to comparatively evaluate the effects of different irrigation needle designs used during endodontic treatment on postoperative pain and to provide information on which needle designs may be more advantageous in clinical applications based on the findings obtained.

Conditions

Lower Molars With Irreversible Pulpitis

Keywords

root canal treatment, conventional needle irrigation, irrigation needle design, postoperative pain

Outcome Measures

Primary Outcomes (1)

• Assessment of postoperative pain with VAS after root canal treatment

  6, 24, 48, 72 hours, and on the 7th day

Study Arms (3)

Group 1

EXPERIMENTAL

For group 1, an open-ended notched irrigation needle (Endo-Top, Cerkamed, Stalowa Wola, Poland)Raito, China)

Procedure: Irrigation

Group 2

EXPERIMENTAL

For group 2, a closed-ended single orifice irrigation needle (Scope Endo Fx Ject, Turkey)

Procedure: Irrigation

Group 3

EXPERIMENTAL

For group 3,a closed-ended double orifice irrigation needle (Double Sideport, Raito, China)

Procedure: Irrigation

Interventions

Irrigation PROCEDURE

Irrigation procedures were performed with needles of different designs, each 30 G, for three different groups

Group 1; Group 2; Group 3

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy patients ranging between 18 and 65 years in age,
• Patients with preoperative pain score ranging from moderate to severe (4-10) on a visual analog scale (VAS, 0-10)
• Mandibular molar teeth were diagnosed with symptomatic irreversible pulpitis

You may not qualify if:

• Patients with systemic diseases,
• Pregnancy or lactation
• Teeth with periapical lesions,
• Teeth that previous root canal treatment,
• Teeth with calcified canals,
• Teeth with periodontal diseases,
• Teeth with sensitivite to percussion and palpation,
• Teeth with bruxism/traumatic occlusion,
• Teeth with crown or root fractures,
• Teeth with internal or external resorption,
• Teeth with immature/open apex,
• Patients who had taken antibiotics in the last two weeks,
• Patients who had taken analgesic or anti-inflammatory drugs within the last 12 hours,
• Patients missing consent and follow-up forms.

Sponsors & Collaborators

• Akdeniz University: lead

Study Sites (1)

AkdenizUniversity

Antalya, Turkey (Türkiye)

Location

Related Publications (1)

• Yersel A, Kirici D. The effect of the design of the irrigation needle used during endodontic treatment on postoperative pain: a randomize clinical trial. Sci Rep. 2026 Jan 7. doi: 10.1038/s41598-025-34420-6. Online ahead of print.

  PMID: 41501119 DERIVED

MeSH Terms

Conditions

Pain, Postoperative

Interventions

Therapeutic Irrigation

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Hydrotherapy; Physical Therapy Modalities; Therapeutics; Rehabilitation; Investigative Techniques

Study Officials

• Damla Kırıcı, Associate Prof

  Akdeniz University

  STUDY CHAIR

• Damla Kırıcı, ASSOCİATE PROF

  AkdenizUniversity

  STUDY CHAIR

• DAMLA KIRICI, ASSOCİATE PROF

  AKDENİZ UNİVERSİTY

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Damla Kırıcı

Study Record Dates

• First Submitted: July 15, 2025
• First Posted: July 23, 2025
• Study Start: January 1, 2023
• Primary Completion: January 1, 2024
• Study Completion: August 1, 2024
• Last Updated: July 23, 2025

Record last verified: 2025-07

Locations

TU (1)