NCT07073716

Brief Summary

the aim of this study is To assess the antioxidant potential by measuring TAC, SOD and MDA responses to aerobic exercise versus phoenix seed in 60 obese sedentary females with symptoms of systemic inflammation. • All subjects will follow the given instructions strictly during the study duration, regarding the assessment and the treatment procedure, all participants will be evaluated under the same environmental conditions

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2025

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 10, 2025

Completed
Same day until next milestone

Study Start

First participant enrolled

July 10, 2025

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 18, 2025

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 10, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

November 10, 2025

Completed
Last Updated

July 18, 2025

Status Verified

July 1, 2025

Enrollment Period

3 months

First QC Date

July 10, 2025

Last Update Submit

July 10, 2025

Conditions

Outcome Measures

Primary Outcomes (3)

  • TAC or total antioxidant capacity (blood test)

    TAC: Determines the total antioxidant capacity of biological samples as a valuable approach to measuring health status under oxidative stress conditions,

    test applied before and after 2 months of the intervention protocol

  • SOD (superoxide dismutase)

    a blood test to determine the amount of SOD in blood and giving a good idea of the overall superoxide detoxifying capacity of a cell or tissue

    Pre- intervention and after 8 weeks of treatment

  • MDA (malondialdehyde)

    blood test that measures Malondialdehyde (MDA) level as a marker of oxidative stress and a contributor to all major diseases by determining the impact of oxidation in normal and cancer cells.

    Pre- intervention and after 8 weeks of treatment

Study Arms (3)

Aerobic exercise

EXPERIMENTAL

20 subjects performed a specialized program of aerobic exercise with frequency of 3-5 times /week

Other: aerobic exercise

phoenix seed

EXPERIMENTAL

20 subjects performed specialized program of phoenix seed consumption

Dietary Supplement: phoenix seed

Aerobic exercise and phoenix seed

EXPERIMENTAL

20 subjects performed the same program of aerobic exercise with same frequency of 3-5 times /weeks combined with the same program of phoenix seed consumption

Combination Product: aerobic exercise+ phoenix seed

Interventions

the exercise protocol was applied following these characteristics * frequency: 3-5 times /week along the whole study period * intensity: 70% of the maximal heart rate (220- age x 70/100) * duration: 50 min (warming up exercise movements (stretching and flexibility) in standing position, active phase of walking on a computerized treadmill, cooling down exercise movements (stretching and flexibility) performed in the seated position. being supervised by two trainers and the researcher. The researcher controlled the heartbeat 2 times through carotid pulse and At the end in order to restore the body to its initial state. all the patients could drink water during their training.

Aerobic exercise
phoenix seedDIETARY_SUPPLEMENT

consuming 2 grams of phoenix seed powder dissolved in about 100 ml water 3 times/day

phoenix seed

a specialized programme of aerobic exercise.the exercise protocol follow these characteristics * frequency: 3-5 times /week along the whole study period * intensity: 70% of the maximal heart rate (220- age x 70/100) * duration: 50 min (warming up exercise movements (stretching and flexibility) in standing position, active phase of walking on a computerized treadmill, cooling down exercise movements (stretching and flexibility) performed in the seated position. being supervised by two trainers and the researcher. The researcher controlled the heartbeat 2 times through carotid pulse and At the end in order to restore the body to its initial state. all the patients could drink water during their training. the specialized program of phoenix seed consumption (consuming 2 grams of phoenix seed powder dissolved in about 100 ml water 3 times/day)

Aerobic exercise and phoenix seed

Eligibility Criteria

Age35 Years - 55 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailsfemales
Healthy VolunteersYes
Age GroupsAdult (18-64)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Central Study Contacts

Zainab Saeed Aly, lecturer at Horus university

CONTACT

nagwa ammar, professor of pharmacognosy

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

July 10, 2025

First Posted

July 18, 2025

Study Start

July 10, 2025

Primary Completion

October 10, 2025

Study Completion

November 10, 2025

Last Updated

July 18, 2025

Record last verified: 2025-07