Compass 3: A Novel Transition Program to Reduce Disability After Stroke
COMPASS 3
2 other identifiers
interventional
520
1 country
2
Brief Summary
This study evaluates a program designed to help individuals transition from inpatient rehabilitation to home following an ischemic or hemorrhagic stroke. Half of the participants will receive a stroke education program while the other half will receive an environmental modifications program.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable stroke
Started Sep 2025
Longer than P75 for not_applicable stroke
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 14, 2025
CompletedFirst Posted
Study publicly available on registry
July 17, 2025
CompletedStudy Start
First participant enrolled
September 29, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 31, 2030
February 13, 2026
February 1, 2026
4.5 years
July 14, 2025
February 12, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Admission to SNF (skilled nursing facility)
Date and days of admission to a skilled nursing facility
From enrollment to 12 months post-discharge from inpatient rehabilitation facility
Study Arms (2)
COMPASS intervention
EXPERIMENTALCOMPASS is a complex intervention that combines 2 evidence-based treatment strategies at a new point of care (transition from inpatient rehabilitation). The objective of home visits by an occupational therapy (OT) practitioner is to remediate barriers in the home and community that influence daily activities and community participation.
Education Program
SHAM COMPARATORA research team member will deliver the program in accordance with "Evidence-Based Educational Guidelines for Stroke Survivors after Discharge Home." Topics may include stroke symptoms, risk factors and preventing stroke recurrence.
Interventions
The data from the baseline assessment will be used to develop an environmental modification intervention plan. Environmental modifications will be installed before discharge if possible. Problem areas addressed are participant specific (tailored), but the process to identify and address the target area is systematic. All participants will receive identical intervention components. The standardized components include assessment, identification of problematic activities (and environmental barriers), identification of solutions for each problem, implementation of solution set selected by the participant, training, and active practice of daily activities in one's own home and community.
The control group will experience the same effects of time and attention in the home but no effect on the outcome of interest.
Eligibility Criteria
You may qualify if:
- Aged ≥55 years at the time of screening
- Acute stroke diagnosis (IS or ICH) verified by the stroke team or medical record
- Independent in activities of daily living (ADLs) prior to stroke (premorbid Modified Rankin Scale score ≤2)
- Plan to discharge to home from an IR
- Capable of giving informed consent which includes compliance with the requirements and duration of participation as listed in the Informed Consent Form (ICF).
You may not qualify if:
- Life expectancy \<6 months
- Cognitive impairment that the participant's stroke team or a research team member believes impairs their ability to provide informed consent or make reasoned choice including the interpretation of the self-rated scales
- Any communication problem that would prevent study completion
- Residence in a congregate living facility
- Not eligible for a therapeutic pass
- Residence outside of the designated catchment area (specific catchment distance to be determined by each site)
- Site investigator's judgment that the participant would not be able to complete research procedures or interventions
- Participation in another research study that in the site investigator's judgment could interfere or conflict with this research study's assessments or interventions
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
University of Missouri
Columbia, Missouri, 65211, United States
Washington University in St. Louis
St Louis, Missouri, 63110, United States
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Susan Stark, PhD
Washington University School of Medicine
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 14, 2025
First Posted
July 17, 2025
Study Start
September 29, 2025
Primary Completion (Estimated)
March 31, 2030
Study Completion (Estimated)
March 31, 2030
Last Updated
February 13, 2026
Record last verified: 2026-02
Data Sharing
- IPD Sharing
- Will share
Final de-identified data will be preserved and shared with the public via WashU Research Data, an institutional repository managed by the Washington University in St. Louis Libraries. Datasets submitted to the data repository undergo curation prior to publication to ensure that the data are functioning, in the appropriate format, and well documented to facilitate long-term FAIRness (findable, accessible, interoperable and reusable). Submissions receive digital object identifiers minted with DataCite, and the library will retain the deposits for a minimum of 10 years.