NCT07066943

Brief Summary

This study evaluates the feasibility, acceptability, and sustainability of MINDxYOU, a self-guided online psychotherapy program designed to reduce stress and improve the mental well-being of healthcare professionals in the Andalusian public health system. The trial uses a hybrid type 3 effectiveness-implementation design, combining the evaluation of implementation outcomes with observation of clinical effects on stress, anxiety, and depression. The intervention includes mindfulness, compassion, and acceptance-based practices delivered in four online modules over eight weeks. The study will be conducted in two phases: an initial hospital-based pilot and a broader rollout across primary care and hospital centers. Results will help identify how digital mental health interventions can be integrated into routine healthcare settings to support professionals working under high stress.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
130

participants targeted

Target at P50-P75 for not_applicable

Timeline
14mo left

Started Nov 2025

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress31%
Nov 2025Jul 2027

First Submitted

Initial submission to the registry

July 4, 2025

Completed
11 days until next milestone

First Posted

Study publicly available on registry

July 15, 2025

Completed
4 months until next milestone

Study Start

First participant enrolled

November 1, 2025

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2027

Last Updated

July 15, 2025

Status Verified

July 1, 2025

Enrollment Period

1.7 years

First QC Date

July 4, 2025

Last Update Submit

July 4, 2025

Conditions

Keywords

Third-wave psychotherapiesmindfulnesshealthcare workers

Outcome Measures

Primary Outcomes (3)

  • Feasibility of Intervention Measure (FIM)

    Includes 4 items designed to measure appropriateness of the intervention. The scale presents 5-point Likert-type scale (1 = completely disagree, 2 = in disagreement, 3 = neither agree nor disagree, 4 = agree and 5 = completely agree). A total score, ranging from 0 to 20, is calculated by totalling the scores from all the items, and higher total values indicate higher level of Feasibility of the intervention

    Post-treatment 10 weeks from baseline

  • System Usability Scale (SUS)

    It is a 10-item questionnaire to measure the usability which qualitatively is related with the quality and acceptability of the intervention. The scale presents 5-point Likert-type scale (0 = never, 1 = almost never, 2 = often, 3 = sometimes and 4 = always). A total score, ranging from 0 to 40, is calculated by totalling the scores from all the items, and higher total values indicate higher level of acceptability of the intervention

    Post-treatment, 10 weeks from baseline

  • Client Satisfaction Questionnaire adapted to Internet-Based interventions (CSQ-I)

    It is an 8-item, 4-point Likert scale questionnaire that assesses the general satisfaction of the participants regarding the received intervention. The total score ranges from 8 to 32.

    Post-treatment 10 weeks from baseline

Secondary Outcomes (6)

  • Perceived Stress Scale (PSS)

    Baseline

  • Perceived Stress Scale (PSS)

    Post-treatment 10 weeks from baseline

  • Patient Health Questionnaire (PHQ-9)

    Baseline

  • Patient Health Questionnaire (PHQ-9)

    Post-treatment 10 weeks from baseline

  • General Anxiety Disorder-7 (GAD-7)

    Baseline

  • +1 more secondary outcomes

Study Arms (1)

MINDxYOU

EXPERIMENTAL

The online program MINDxYOU is based on the principles of 'third wave' psychotherapies, such as the promotion of wellbeing through the practice of mindfulness, compassion, acceptance, and spirituality and the estimated time for completing the whole program is 8 weeks

Behavioral: MINDxYOU

Interventions

MINDxYOUBEHAVIORAL

The online program MINDxYOU is based on the principles of 'third wave' psychotherapies and it is an online program particularly addressed at healthcare providers which will both monitor and support the individual's mental health. The program is self-administered and will be delivered via the Internet and available via smartphone, tablet, and personal computer.

MINDxYOU

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Being a current healthcare professional.
  • Age between 18 and 70 years.
  • Ability to understand Spanish.
  • Digital literacy and access to a smartphone, tablet or computer with internet connection.
  • Continuity in the same workplace for at least 6 months (6) signing the informed consent to participate in the study.

You may not qualify if:

  • Diagnosis of serious mental illness.
  • Suicidal ideation.
  • Substance abuse or related disorders.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Regional Universitario de Málaga Plaza del Hospital Civil s/n, Pabellón 4, 1ª Planta, 29009, Málaga

Málaga, 29009, Spain

Location

Related Publications (2)

  • Lopez-Del-Hoyo Y, Fernandez-Martinez S, Perez-Aranda A, Monreal-Bartolome A, Barcelo-Soler A, Camarero-Grados L, Armas-Landaeta C, Guzman-Parra J, Carbonell V, Campos D, Chen X, Garcia-Campayo J. Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Randomized Trial. J Med Internet Res. 2025 Feb 3;27:e59653. doi: 10.2196/59653.

  • Lopez-Del-Hoyo Y, Fernandez-Martinez S, Perez-Aranda A, Barcelo-Soler A, Guzman-Parra J, Varela-Moreno E, Campos D, Monreal-Bartolome A, Beltran-Ruiz M, Moreno-Kustner B, Mayoral-Cleries F, Garcia-Campayo J. Effectiveness and implementation of an online intervention (MINDxYOU) for reducing stress and promote mental health among healthcare workers in Spain: a study protocol for a stepped-wedge cluster randomized trial. BMC Nurs. 2022 Nov 10;21(1):308. doi: 10.1186/s12912-022-01089-5.

Related Links

Study Officials

  • Gloria Margarita Guerrero Pertíñez, PhD

    Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud

    PRINCIPAL INVESTIGATOR
  • José Guzmán Parra, PhD

    Hospital Regional Universitario de Málaga Plaza del Hospital Civil s/n, Pabellón 4, 1ª Planta, 29009, Málaga

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Gloria Margarita Guerrero Pertíñez, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 4, 2025

First Posted

July 15, 2025

Study Start

November 1, 2025

Primary Completion (Estimated)

July 1, 2027

Study Completion (Estimated)

July 1, 2027

Last Updated

July 15, 2025

Record last verified: 2025-07

Data Sharing

IPD Sharing
Will not share

IPD will not be shared due to ethical and privacy considerations. The data collected are sensitive mental health measures from healthcare professionals, and the protocol does not include consent for sharing individual-level data with external researchers. Only aggregated results will be made publicly available.

Locations