Effects of Egoscue Exercises in Patients With Knee Osteoarthritis

NCT07063953 | Not Yet Recruiting

• 1 other identifier: REC/RCR &AHS/24/0146 Momina
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

Knee osteoarthritis (KOA) is a chronic, debilitating illness with multiple etiologies that affects the entire knee joint. It is a leading cause of disability among the elderly population and necessitates effective interventions beyond pharmacotherapy due to the associated risks. This study will address the existing literature gap by focusing on a novel therapeutic approach known as 'Egoscue Exercises', for managing knee osteoarthritis in the affected population.

Conditions

Knee Osteoarthritis

Keywords

Pain; Physical Function; Range of motion

Outcome Measures

Primary Outcomes (3)

• Range of Motion

  The range of motion will be measured by using Universal Goniometer, which is a highly reliable and valid tool. It will measure knee joint range of motion which includes knee flexion and extension.

  upto 4 weeks

• Western Ontario and McMaster Universities Arthritis (WOMAC) index

  WOMAC Index is widely used in the evaluation of Knee Osteoarthritis. It is a 24 item questionnaire divided into 3 subscales: 1. Pain (5 items): during walking, using stairs, in bed, sitting or lying, and standing upright 2. Stiffness (2 items): after first waking and later in the day 3. Physical Function (17 items): using stairs, rising from sitting, standing, bending, walking, getting in / out of a car, shopping, putting on / taking off socks, rising from bed, lying in bed, getting in / out of bath, sitting, getting on / off toilet, heavy domestic duties, light domestic duties.

  upto 4 weeks

• Numerical Pain Rating Scale (NPRS)

  The Numeric Pain Rating Scale (NPRS) is perhaps the most frequently applied scale used to quantify pain intensity in the clinical setting. It is an 11-point numeric scale, ranging from 0 indicating no pain to 10 indicating worst pain imaginable

  upto 4 weeks

Study Arms (2)

Egoscue Exercises

EXPERIMENTAL

Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises

Other: Egoscue Exercises

Standard Physical Therapy

ACTIVE COMPARATOR

Hot pack \& Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises

Other: Standard Physical Therapy

Interventions

Standard Physical Therapy OTHER

Hot pack \& Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises

Standard Physical Therapy

Egoscue Exercises OTHER

Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises

Egoscue Exercises

Eligibility Criteria

• Age: 45 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age group between 45 and 65 years ,
• Both genders male and female ,
• BMI ˃ 25 , and Knee OA clinically or radiologically diagnosed by Kellgren-Lawrence Method, Grade II and III

You may not qualify if:

• Age less than 45 years or older than 65 years,
• BMI \< 25, Knee OA in grade I and IV, and
• Patients on steroid therapy and intra articular injection

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Basharat Hospital, Sahiwal

Sahiwal, Punjab Province, 54000, Pakistan

Location

Related Publications (6)

• Sharma L. Osteoarthritis of the Knee. N Engl J Med. 2021 Jan 7;384(1):51-59. doi: 10.1056/NEJMcp1903768. No abstract available.

  PMID: 33406330 BACKGROUND

• Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020 Nov 26;29-30:100587. doi: 10.1016/j.eclinm.2020.100587. eCollection 2020 Dec.

  PMID: 34505846 BACKGROUND

• Giorgino R, Albano D, Fusco S, Peretti GM, Mangiavini L, Messina C. Knee Osteoarthritis: Epidemiology, Pathogenesis, and Mesenchymal Stem Cells: What Else Is New? An Update. Int J Mol Sci. 2023 Mar 29;24(7):6405. doi: 10.3390/ijms24076405.

  PMID: 37047377 BACKGROUND

• Kondal S, Kulkarni V, Gaikwad A, Kharat A, Pant A. Automatic Grading of Knee Osteoarthritis on the Kellgren-Lawrence Scale from Radiographs Using Convolutional Neural Networks [Internet]. arXiv.org. 2020 [cited 2024 Jun 25].

  BACKGROUND

• Yunus MHM, Nordin A, Kamal H. Pathophysiological Perspective of Osteoarthritis. Medicina (Kaunas). 2020 Nov 16;56(11):614. doi: 10.3390/medicina56110614.

  PMID: 33207632 BACKGROUND

• Siddiq MAB, Clegg D, Jansen TL, Rasker JJ. Emerging and New Treatment Options for Knee Osteoarthritis. Curr Rheumatol Rev. 2022;18(1):20-32. doi: 10.2174/1573397117666211116111738.

  PMID: 34784876 BACKGROUND

MeSH Terms

Conditions

Osteoarthritis, Knee; Pain

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Samrood Akram, PhD*

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Samrood Akram, PhD Scholar

CONTACT

03324806143; samrood.akram@riphah.edu.pk.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 3, 2025
• First Posted: July 14, 2025
• Study Start: July 1, 2025
• Primary Completion: September 1, 2025
• Study Completion: October 1, 2025
• Last Updated: July 14, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)