Integrated Trunk Stabilization With Osteoarthritis Rehabilitation in Knee-Spine Syndrome

NCT07484594 | Not Yet Recruiting DMC

• 1 other identifier: Tooba Rauf
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the effects of integrating trunk stabilization exercises with conventional rehabilitation in patients with knee-spine syndrome. It further examines whether improving trunk stability can reduce knee pain and enhance functional outcomes in knee osteoarthritis

Conditions

Knee Osteoarthritis

Keywords

Knee Osteoarthritis; Knee-Spine Syndrome; Trunk Exercise

Outcome Measures

Primary Outcomes (2)

• Visual Analogue Scale

  The Visual Analog Scale (VAS) is a simple and reliable tool for assessing pain intensity on a continuous visual scale. The extreme limits of pain are represented by the straight line's ends, where 0 indicates no pain, and 10 indicates the worst pain a person has ever felt.

  6 weeks

• Western Ontario and McMaster Universities Arthritis Index (WOMAC)

  It is widely used in the evaluation of knee osteoarthritis to assess activities of daily living, functional mobility, gait, general health, and quality of life. It has 24 items divided into 3 subscales: pain (5 items), stiffness (2 items), and physical function (17 items). The scores range from 0 to 4 for each subscale. The score ranges from 0 to 96, where zero indicates no pain, stiffness, and functional limitation. Higher scores indicate worse pain, stiffness, and functional limitation.

  6 weeks

Secondary Outcomes (4)

• Range Of motion (ROM)

  6 weeks

• Time-Up-and-Go (TUG)

  6 weeks

• Oswestry Disability Index (ODI)

  6 weeks

• Flexicurve (Lumbar Range of motion)

  6 weeks

Study Arms (2)

Trunk Stabilization exercises with conventional Rehab

EXPERIMENTAL

The intervention will include the conventional knee osteoarthritis rehabilitation protocol comprising mobilization, stretching, and strengthening exercises, along with the following trunk stabilization exercises performed for 6 repetition followed by 30 second rest : 1. Prone extension 2. Back bridge 3. Unilateral back bridge 4. Sideways step-up 5. Bird dog

Other: Trunk Stabilization exercises with conventional Rehab

Conventional Rehabilitation

OTHER

The conventional rehabilitation protocol for knee osteoarthritis included Maitland's mobilization performed at a rate of 2-3 oscillations per second for 2 minutes, followed by stretching exercises held for 30 seconds across three sets. Muscle strengthening exercises were also incorporated, consisting of 10 repetitions with a 15-second hold, performed over four sets.

Other: Conventional Rehabilitation

Interventions

Trunk Stabilization exercises with conventional Rehab OTHER

The protocol for will be followed for 6 weeks, where individuals will perform trunk stabilization exercises with conventional rehabilitation for knee osteoarthritis.

Trunk Stabilization exercises with conventional Rehab

Conventional Rehabilitation OTHER

The protocol for will be followed for 6 weeks, where conventional rehabilitation for knee osteoarthritis will be implemented.

Conventional Rehabilitation

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 40-60 years
• Both Genders
• Bilateral Knee osteoarthritis diagnosed according to the American College of Rheumatology Clinical Classification system
• Kellgren \& Lawrence grade 2 and 3 with complaint of pain, crepitations, stiffness and bony enlargement
• History of backpain for the past 3 months with no complaint of radiating pain
• Able to walk independently/unaided

You may not qualify if:

• Kellgren \& Lawrence grade 4
• Intra-articular corticosteroid injections in the last 3 months or hyaluronic knee injection in the previous 6 months.
• History of lower limb or lumbar trauma/surgery, presence of fracture or deformity, or planned surgery within the study period
• Lumbar pathologies, for example, spondylolisthesis, ankylosing spondylitis, or any diagnosed severe cardiovascular, pulmonary, neurological, or psychological disease or impairment except lumbar spondylosis
• BMI\>30
• Presence of infection, cauda equina syndrome, or meningitis

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Bahria Active

Rawalpindi, Pakistan

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Officials

• Suman Sheraz, PhD

  Riphah International University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Suman Sheraz, PhD

CONTACT

03335646361; suman.sheraz@riphah.edu.pk

Imran Amjad, PhD

CONTACT

03324390125; imran.amjad@riphah.edu.pk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 16, 2026
• First Posted: March 20, 2026
• Study Start: April 1, 2026
• Primary Completion (Estimated): July 15, 2026
• Study Completion (Estimated): August 15, 2026
• Last Updated: May 6, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)