NCT06457529

Brief Summary

Cervical radiculopathy is characterized by neurological dysfunction caused by compression and inflammation of the spinal nerves or nerve roots of the cervical spine. Rolotherapy is a regenerative therapeutic method that consists of injecting irritant solutions into the injured areas.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Oct 2023

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2023

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

June 10, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 13, 2024

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2024

Completed
Last Updated

June 13, 2024

Status Verified

June 1, 2024

Enrollment Period

7 months

First QC Date

June 10, 2024

Last Update Submit

June 10, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Neck Disability Index

    The NDI has become a standard instrument for measuring self-rated disability due to neck pain and is used by both clinicians and researchers. Each of the 10 items scores from 0 to 5. The maximum score is 50. The obtained score can be multiplied by two to produce a percentage score

    12 Months

  • WHO Quality of Life

    The QOLS is a reliable and valid instrument for measuring quality of life from the perspective of the patient. It focuses on domains that come from the qualitative descriptions of a wide range of adults across gender, cultural and language groups.Each individual item of the WHOQOL-BREF is scored from 1 to 5 on a response scale, which is stipulated as a five-point ordinal scale. The scores are then transformed linearly to a 0-100-scale (16, 17). The physical health domain includes items on mobility, daily activities, functional capacity, energy, pain, and sleep

    12 months

Study Arms (2)

conventional treatment with Prolotherapy

EXPERIMENTAL
Diagnostic Test: conventional treatment with Prolotherapy

Dry Needling and conventional treatment

OTHER
Other: Dry Needling and conventional treatment

Interventions

Group A got prolotherapy along with conven¬tional treatment, which includes ultrasonic therapy for 10 minutes. The intensity will be 3MHz at 1.0 watts/cm2. Prolotherapy is an injection treatment used to relieve pain. Your healthcare provider will inject a small amount of an irritant into your body. Dextrose (sugar) solution is the most commonly injected irritant. Proponents of prolotherapy claim it relieves pain by jumpstarting your body's natural healing abilities.

conventional treatment with Prolotherapy

Group B Subjects in Group B will get Dry Needling along with conventional treatment, which includes ultrasonic therapy for 10 minutes. The intensity will be 3MHz at 1.0 watts/cm2. Trigger-point dry needling is an invasive procedure where a fine needle or acupuncture needle is inserted into the skin and muscle

Dry Needling and conventional treatment

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Age group between 20-50 years
  • Both male and female
  • Unilateral pain starting in the cervical spine and radiating to the upper limb.
  • Pain aggravated by upper limb movement
  • Restricted range of motion of arm

You may not qualify if:

  • History of Spinal infection
  • Spinal Cord Injury
  • History of Vertebral tumor and factures
  • History of cervical or intracranial surgery
  • History of Radiating pain to bilateral upper limb.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Iqbal Mahmooda Hospital, Iffat Anwar Medical Complex and Life line Hospital

Lahore, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Radiculopathy

Interventions

Dry Needling

Condition Hierarchy (Ancestors)

Peripheral Nervous System DiseasesNeuromuscular DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

Complementary TherapiesTherapeuticsPhysical Therapy Modalities

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 10, 2024

First Posted

June 13, 2024

Study Start

October 1, 2023

Primary Completion

May 1, 2024

Study Completion

September 30, 2024

Last Updated

June 13, 2024

Record last verified: 2024-06

Data Sharing

IPD Sharing
Will not share

Locations