Role of Nerve Mobilizations in Decreasing Pain and Disability Among Patients With Cervical Radiculopathy

NCT04896749 | Completed

• 1 other identifier: IRB-UOL-FAHS/719-VI/2020
• Study Type: interventional
• Target: 64
• Locations: 1 country
• Sites: 1

Brief Summary

Objective of the study is to find out the effectiveness of nerve mobilization in patients with cervical radiculopathy. It is a single blinded randomized controlled trial using non-probability convenient sampling. Data is collected from University Physical therapy and Rehabilitation Clinic, University of Lahore, Pakistan. Alternate hypothesis: There is a significant role of nerve mobilizations in decreasing pain and disability among patients with cervical radiculopathy. Null hypothesis: There is no significant role of nerve mobilizations in decreasing pain and disability among patients with cervical radiculopathy. .

Conditions

Cervical Radiculopathy

Keywords

cervical radiculopathy; neuromobilization; pain; disability

Outcome Measures

Primary Outcomes (3)

• Upper extremity functional index (assessing change in ability to do activities with upper limb at baseline and at 4th week of treatment)

  It is a patient reported outcome measure used to assess the functional impairment in individuals with upper limb dysfunction. Total score is 80. Greater the score, better the condition of patients.

  Baseline and at 4th week

• Numeric pain rating scale (to assess change in pain at between baseline and at 4th week of treatment)

  Used for scoring pain level of individual. it is scored 0 to ten.Zero being the lowest pain level, 10 being worst pain level.The patient is asked to make three pain ratings, corresponding to the pain experienced over the past 24 hours. The average of the 3 ratings was used to represent the patient's level of pain over the previous 24 hours.

  Baseline and at 4th week

• Neck Disability Index scale (to assess the change in disability due to neck pain at baseline and at 4th week of treatment)

  This scale is used for accessing how the neck pain is affecting the ability to manage everyday life activities.The NDI can be scored as a raw score or doubled and expressed as a percent. Each section is scored on a 0 to 5 rating scale, in which zero means 'No pain' and 5 means 'Worst imaginable pain'. Points of total 10 questions are summed to a total score.Greater score indicates greater disability.

  Baseline and at 4th week

Study Arms (2)

Group A/ Nerve mobilization group

EXPERIMENTAL

In this group, patients will receive nerve mobilization exercises along with routine physical therapy. Patients will also be given home plan for cervical isometric exercises.

Other: Nerve mobilization

Group B/ Conventional physical therapy group

ACTIVE COMPARATOR

In this group, patients will receive routine physical therapy and also given home plan for cervical isometric exercises

Other: Conventional physical therapy

Interventions

Nerve mobilization OTHER

Moist pack all over cervical spine for 10 minutes. TENS for 10 minutes at frequency of 60 Hz with 2 electrodes. Cervical traction for 10 minutes with 7 sec hold and 5 sec rest time. Cervical isometric exercises with 7 sec hold and 30 repetitions in each direction twice a day. Median, ulnar and radial nerve stretch with 3 sets of 10 repetitions , with 3 sec hold at final stretched position. Following nerve mobilizations are used in experimental group/group A: Median Nerve: Glenohumeral abduction, wrist extension, supination, glenohumeral lateral rotation, elbow extension, neck lateral bending to opposite side. Radial Nerve: Glenohumeral depression, elbow extension, whole arm internal rotation, wrist flexion Ulnar Nerve: Wrist extension, forearm pronation elbow flexion, glenohumeral lateral rotation, glenohumeral depression, shoulder abduction each with 3 sets of 10 repetitions , with 3 sec hold at final stretched position.

Group A/ Nerve mobilization group

Conventional physical therapy OTHER

Moist pack for 10 minutes. TENS for 10 minutes at frequency of 60 Hz with 2 electrodes. Cervical traction for 10 minutes with 7 sec hold and 5 sec rest time. Cervical isometric exercises with 7 sec hold and 30 repetitions in each direction twice a day.

Also known as: Routine physical therapy

Group B/ Conventional physical therapy group

Eligibility Criteria

• Age: 20 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Male and female patients with age between 20 to 45 years
• Patients having pain for more than 4 months
• Patients having positive upper limb neurodynamic test
• Patient with positive spurling test.

You may not qualify if:

• Patients with trauma of upper limb and cervical spine
• Dizziness
• Upper limb circulatory disturbance
• Malignancy
• Patients with bilateral symptoms

Sponsors & Collaborators

• University of Lahore: lead

Study Sites (1)

University Physical Therapy and Rehabilitation Clinic

Lahore, Punjab Province, 54000, Pakistan

Location

MeSH Terms

Conditions

Radiculopathy; Pain

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Momna Asghar, MSPTN

  University of Lahore

  PRINCIPAL INVESTIGATOR

• Muhammad Haider Ullah Khan, MSPTN

  University of Lahore

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: April 8, 2021
• First Posted: May 21, 2021
• Study Start: June 1, 2021
• Primary Completion: August 13, 2021
• Study Completion: August 16, 2021
• Last Updated: November 30, 2021

Record last verified: 2021-11

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP
• Time Frame: Data will be available after the publication of the study for at least two years
• Access Criteria: Data can be accessed by emailing the principal investigator

Locations

PA (1)