Association Between Radial Artery Access Point and Radial Artery Spasm

NCT07060820 | Completed

• 1 other identifier: MMP-KAR-VA-01
• Study Type: interventional
• Target: 380
• Locations: 1 country
• Sites: 1

Brief Summary

This prospective clinical study aims to investigate whether the puncture site distance from the radial styloid process affects the incidence of radial artery spasm (RAS) during coronary angiography. Patients undergoing coronary angiography via radial access will be randomized into two groups based on the puncture site distance: 0-20 mm and \>21 mm from the styloid process. The procedure will be performed by experienced interventional cardiologists using standard techniques and medications. The primary goal is to determine if a specific puncture site reduces the incidence of RAS, which is a common complication during transradial procedures. The study will also record procedural details and monitor for other complications to identify the optimal puncture site for reducing RAS and improving patient comfort.

Conditions

Coronary Artery Disease; Radial Artery Spasm

Keywords

Transradial Access; Radial Artery Spasm; Coronary Angiography

Outcome Measures

Primary Outcomes (1)

• Radial Artery Spasm during Transradial Coronary Angiography

  İnsidance of Radial Artery Spasm during Transradial Coronary Angiography

  During the procedure

Secondary Outcomes (1)

• Incidence of access site complications

  Within 5 days post-procedure

Study Arms (2)

0-20 mm Puncture Distance Group

EXPERIMENTAL

Radial artery puncture performed 0-20 mm proximal to the radial styloid process during transradial coronary angiography to evaluate its effect on the incidence of radial artery spasm (RAS).

Procedure: Radial Artery Puncture at 0-20 mm

21 mm Puncture Distance Group

EXPERIMENTAL

Radial artery puncture performed 21-40 mm proximal to the radial styloid process during transradial coronary angiography to evaluate its effect on the incidence of radial artery spasm (RAS).

Procedure: Radial Artery Puncture at >21 mm

Interventions

Radial Artery Puncture at 0-20 mm PROCEDURE

Radial artery puncture performed 0-20 mm proximal to the radial styloid process during transradial coronary angiography to evaluate its impact on the incidence of radial artery spasm (RAS).

0-20 mm Puncture Distance Group

Radial Artery Puncture at >21 mm PROCEDURE

Radial artery puncture performed at a distance greater than 21 mm proximal to the radial styloid process during transradial coronary angiography to evaluate its impact on the incidence of radial artery spasm (RAS).

21 mm Puncture Distance Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults aged 18 years and older. Patients scheduled for coronary angiography via transradial access. Patients with a palpable radial artery pulse. Patients with a normal Allen test.

You may not qualify if:

• Abnormal Allen test results. Absence of palpable radial artery pulse. History of prior transradial coronary angiography with hemodynamic instability. Patients with severe comorbid conditions precluding safe participation in the study.

Sponsors & Collaborators

• Mersin Medicalpark Hastanesi: lead

Study Sites (1)

VM Medicalpark Mersin Hospital

Mersin, Mezitli, 33200, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Study Officials

• Vedat ASLAN, MD

  Toros University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 2, 2025
• First Posted: July 11, 2025
• Study Start: July 3, 2025
• Primary Completion: December 31, 2025
• Study Completion: January 15, 2026
• Last Updated: January 21, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)