Brief Summary

This study aims to enhance the Healthy Minds Program (HMP) app by developing and testing a personalized, data-driven approach to optimize long-term well-being. 1100 participants will be enrolled and on study for up to 4 months (4 week intervention plus 3 month follow-up).

Trial Health

On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

1,500

participants targeted

Target at P75+ for not_applicable

Timeline

13mo left

Started Jul 2025

Typical duration for not_applicable

Geographic Reach

1 country

1 active site

Status

recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

1.9 years study duration

Study Progress43%

Jul 2025Jun 2027

First Submitted

Initial submission to the registry

June 24, 2025

Completed

10 days until next milestone

First Posted

Study publicly available on registry

July 4, 2025

Completed

16 days until next milestone

Study Start

First participant enrolled

July 20, 2025

Completed

1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2027

Expected

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2027

Last Updated

December 8, 2025

Status Verified

September 1, 2025

Enrollment Period

1.9 years

First QC Date

June 24, 2025

Last Update Submit

December 1, 2025

Conditions

Well-Being, Psychological

Keywords

personalized well-beingHMP appHealthy Minds Program

Outcome Measures

Primary Outcomes (1)

Change in PHQ-9
PHQ-9 is a 9 item questionnaire where participants report how often in the past 2 weeks they were bothered by specific problems. It is scored on a 4-point Likert scale, where 0=not at all and 4=nearly every day. Scores range from 0-36, where higher scores indicate more depressive symptoms.
Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up (up to 4 months on study)

Secondary Outcomes (27)

Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Depression
Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up (up to 4 months on study)
Change in PROMIS Anxiety Score
Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up (up to 4 months on study)
Acceptability of Intervention Measure
week 4 (of intervention period)
Change in Growth Mindset Scale for Well-Being
Baseline, week 4 (of intervention period), and 3 month follow-up (up to 4 months on study)
HMP engagement measure
Week 4 (of intervention period), and 3 month follow-up (up to 4 months on study)
+22 more secondary outcomes

Other Outcomes (6)

Change in Beck Depression Inventory Item 9 Score
Baseline, week 1, week 2, week 3, week 4 (of intervention period), and 3 month follow-up (up to 4 months on study)
Change in Mindfulness-Based Program - Meditation-Related Adverse Effects Scale (MBP-MRAES)
week 4 (of intervention period), and 3 month follow-up (up to 4 months on study)
Lasting Effects Questionnaire
3-month follow-up (up to 4 months on study)
+3 more other outcomes